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System for quantifying blood flow in tissue with periodic updating of tissue baseline conditions

  • US 20030219719A1
  • Filed: 04/04/2003
  • Published: 11/27/2003
  • Est. Priority Date: 04/05/2002
  • Status: Active Grant
First Claim
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1. A method for determining perfusion in living tissue comprising the steps of:

  • (1) establishing baseline criteria, comprising (A) determining an unperturbed temperature of the tissue;

    (B) causing the temperature of the tissue to change from a first unperturbed temperature to a second temperature different from said first temperature for a time period, and (C) determining a value or values for one or more thermal properties of tissue during a first selected portion of said time period;

    (2) calculating a perfusion value for the tissue at a second selected portion of said time period using said thermal property value or values, and (3) evaluating one or more physiological and artifactual conditions to determine if baseline criteria established by step (1) are materially affected by said conditions and if so repeating step (1).

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