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Genes and polymorphisms associated with cardiovascular disease and their use

  • US 20030224418A1
  • Filed: 03/27/2003
  • Published: 12/04/2003
  • Est. Priority Date: 03/09/2001
  • Status: Abandoned Application
First Claim
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1. A method for detecting the presence or absence in a subject of at least one allelic variant of a polymorphic region of a gene associated with cardiovascular disease, comprising:

  • the step of detecting the presence or absence of an allelic variant of a polymorphic region of a cytochrome C oxidase subunit VIb (COX6B) gene of the subject that is associated with high serum cholesterol or an allelic variant of a polymorphic region of a N-acetylglucosaminyl transferase component GPI-1 (GPI-1) gene of the subject that is associated with low serum high density lipoprotein (HDL).

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