Sulfatase inhibiting progestogen-only contraceptive regimens

• US 20030225047A1
• Filed: 03/11/2003
• Published: 12/04/2003
• Est. Priority Date: 03/11/2002
• Status: Abandoned Application

• Current Assignee: Janssen Pharmaceutica NV (Johnson & Johnson)
• Original Assignee: Janssen Pharmaceutica NV (Johnson & Johnson)
• Inventors: Friedman, Andrew Joseph, Caubel, Patrick Michel
• Application Number:
  US10/385,867
• Publication Number:
  US 20030225047A1
• Time in Patent Office: Days
• US Class Current: 514/170
• CPC Class Codes: A61K 31/567 substituted in position 17 alpha, e.g. mestranol, norethandrolone
• CPC Class Codes: A61K 9/0034 Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
• CPC Class Codes: A61K 9/0036 Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
• CPC Class Codes: A61K 9/7023 Transdermal patches and similar drug-containing composite devices, e.g. cataplasms galenical aspects of iontophoretic devices A61K9/0009; microneedle arrays A61K9/0021; buccal patches A61K9/006
• CPC Class Codes: A61P 15/18 Feminine contraceptives
• CPC Class Codes: A61P 43/00 Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
• CPC Class Codes: A61P 5/32 Antioestrogens

Abstract

A method of contraception is disclosed comprising the step of administering to a menstruating female a cycle of contraceptive therapy, said cycle of therapy including the continuous administration for the length of the cycle of a potent sulfatase inhibiting progestogen in a contraceptively effective and breast protecting dose, in the absence of the administration of an estrogen.

Claims

1. A method of contraception comprising the step of administering to a menstruating female a cycle of contraceptive therapy, said cycle of therapy including the continuous administration for the length of the cycle of a potent sulfatase inhibiting progestogen in a contraceptively effective and breast protecting dose, in the absence of the administration of an estrogen.

2. A contraceptive therapy unit for administration to a menstruationg female comprising a cycle of separate dosage units adapted for successive daily oral administration for the length of the cycle, wherein said dosage units contain, in admixture with a pharmaceutically acceptable carrier, a potent sulfatase inhibiting progestogen in a contraceptively effective and breast protecting dose, in the absence of an estrogen.

3. A contraceptive therapy unit for administration to a menstruationg female comprising a cycle of transdermal patches adapted for successive administration for the length of the cycle, wherein said transdermal patches contain, in a suitable matrix, a potent sulfatase inhibiting progestogen in a contraceptively effective and breast protecting dose, in the absence of an estrogen.

4. A contraceptive therapy unit for administration to a menstruationg female comprising a cycle of vaginal rings adapted for successive administration for the length of the cycle, wherein the vaginal rings contain, in a suitable matrix, a potent sulfatase inhibiting progestogen in a contraceptively effective and breast protecting dose, in the absence of an estrogen.