Method and device for measuring blood gas parameters

• US 20030225341A1
• Filed: 05/30/2003
• Published: 12/04/2003
• Est. Priority Date: 05/31/2002
• Status: Active Grant

• Current Assignee: Roche Diagnostics Operations Incorporated (Roche Holding AG)
• Original Assignee: Roche Diagnostics Operations Incorporated (Roche Holding AG)
• Inventors: Huemer, Herfried, Ruether, Horst
• Granted Patent: US 7,491,175 B2
• Time in Patent Office: Days
• US Class Current: 600/549
• CPC Class Codes: A61B 5/0008 Temperature signals
• CPC Class Codes: A61B 5/14539 for measuring pH
• CPC Class Codes: A61B 5/1473 invasive, e.g. introduced into the body by a catheter A61B5/1482 takes precedence
• CPC Class Codes: G01N 33/4925 measuring blood gas content, e.g. O2, CO2 , HCO3

Abstract

The invention relates to a method and device for measuring blood gas parameters, preferably pH, pCO₂, and pO₂, in a blood sample, where the blood sample of a patient is fed into at least one measuring cell of an analyzer. In order to obtain accurate values for the blood gas parameters even in cases where the temperature of the patient deviates from normal temperature, the temperature of the patient or blood sample is measured upon sample withdrawal, and the measured temperature is transmitted to the analyzer or is recorded by the analyzer, and the temperature of the measuring cell of the analyzer is adjusted to the measured temperature by cooling or heating.

Claims

1. A method for measuring blood gas parameters, in a blood sample, comprising the steps of:

measuring the temperature of a patient or the temperature of the blood sample upon sample withdrawal,

feeding the blood sample of the patient into at least one measuring cell of an analyzer,

transmitting the measured temperature to the analyzer, and

for measuring said blood gas parameters adjusting the at least one measuring cell of the analyzer to the measured temperature by heating or cooling said measuring cell.

2. A method according to claim 1, wherein the measuring cell is cooled or heated to the measured temperature before the blood sample is entered into the analyzer, and wherein sample entry is enabled only after said measured temperature is reached.

3. A method according to claim 1, wherein the blood or patient temperature is measured by a temperature probe placed in or on the patient and the temperature data are transmitted automatically to the analyzer.

4. A method according to claim 1, wherein the temperature of the measuring cell is continually adjusted synchronously with the actual temperature measured.

5. A method according to claim 1, wherein the temperature of the measuring cell of the analyzer is regulated in a range from 22°

C. to 40°

C., depending on the temperature measured.

6. A method according to claim 5, wherein the transmission of the measured temperature to the analyzer is performed via cable, via IF signal, or via RF signal.

7. A method according to claim 1, wherein at least one blood gas parameter of a group consisting of pH, pCO₂, and pO₂ is measured.

8. An analyzer for measuring blood gas parameters in a blood sample, with at least one thermostabilized measuring cell, wherein a regulating and control unit is provided, which permits the temperature of the measuring cell to be regulated in a range from 22°

C. to 40°

C., depending on blood sample temperature or a patient temperature measured upon sample withdrawal.

9. An analyzer according to claim 8, wherein the analyzer is provided with a locking device on a sample input element, which is controlled by the regulating and control device and enables sample input only when measuring cell temperature is equal to the blood sample temperature or patient temperature measured.

10. An analyzer according to claim 8, wherein the regulating and control unit is connected to a temperature probe placed in or on the patient, and wherein a cable or wireless link is provided for data transmission to the regulating and control unit.