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Sustained release metoprolol formulations

  • US 20030228361A1
  • Filed: 04/07/2003
  • Published: 12/11/2003
  • Est. Priority Date: 04/05/2002
  • Status: Abandoned Application
First Claim
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1. A sustained release oral solid dosage form comprising:

  • a sustained release matrix comprising from about 12.5 to about 400 mg of metoprolol tartrate and a sustained release excipient;

    said oral dosage form providing a mean Cmax of metoprolol from about 10 ng/ml to about 40 ng/ml when the dosage form contains 100 mg metoprolol tartrate;

    said dosage form providing a therapeutic effect for about 24 hours after oral administration.

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