DNA/RNA as a write/read medium

• US 20030228598A1
• Filed: 03/19/2003
• Published: 12/11/2003
• Est. Priority Date: 03/25/2002
• Status: Abandoned Application

• Current Assignee: Lawrence Livermore National Security LLC (Government of the United States of America)
• Original Assignee: Regents of the University of California (University of California)
• Inventors: Mariella, Raymond P. Jr.
• Application Number:
  US10/393,637
• Publication Number:
  US 20030228598A1
• Time in Patent Office: Days
• US Class Current: 435/6
• CPC Class Codes: B82Y 10/00 Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
• CPC Class Codes: G06N 3/123 DNA computing
• CPC Class Codes: G11C 13/0019 comprising bio-molecules

Abstract

A system for writing and/or reading information using DNA. The information is translated into at least one information containing DNA sequence. At least one basic DNA sequence is preselected. A DNA molecule of user-defined sequence that contains said at least one information containing DNA sequence and said at least one basic DNA sequence is synthesized.

Claims

1. A method of writing and/or reading information using DNA, comprising the steps of:

translating said information into at least one information containing DNA sequence,

preselecting at least one basic DNA sequence,

synthesizing a DNA molecule of user-defined sequence that contains said at least one information containing DNA sequence and said at least one basic DNA sequence.

2. The method of writing and/or reading information using DNA of claim 1 wherein said step of translating said information into at least one information containing DNA sequence comprises using a computer program to translate said information into at least one information containing DNA sequence.

3. The method of writing and/or reading information using DNA of claim 1 wherein said step of preselecting at least one basic DNA sequence comprises using a computer program to preselect at least one basic DNA sequence.

4. The method of writing and/or reading information using DNA of claim 1 wherein said steps of translating said information into at least one information containing DNA sequence and preselecting at least one basic DNA sequence compris using computational techniques to break said sequences into fragments of defined size and said step of synthesizing a DNA molecule of user-defined sequence comprises assembling said fragments into said DNA molecule of user-defined sequence.

5. The method of writing and/or reading information using DNA of claim 1 wherein pre-defined strings of DNA bases are located before and after said at least one information containing DNA sequence in said DNA molecule of user-defined sequence.

6. The method of writing and/or reading information using DNA of claim 1 wherein said steps of synthesizing a DNA molecule of user-defined sequence comprises providing a pre-defined, double-stranded, sequence of DNA with a single-stranded overhang, tethered said pre-defined, double-stranded, sequence of DNA with a single-stranded overhang, and lengthening said pre-defined, double-stranded, sequences of DNA by the addition of user-selected, single stranded DNA sequences.

7. The method of writing and/or reading information using DNA of claim 1 wherein said steps of synthesizing a DNA molecule of user-defined sequence comprises providing a pre-defined, double-stranded, sequence of DNA with a single-stranded overhang, tethered said pre-defined, double-stranded, sequence of DNA with a single-stranded overhang with a bead, and lengthening said pre-defined, double-stranded, sequences of DNA by the addition of user-selected, single stranded DNA sequences.

8. The method of writing and/or reading information using DNA of claim 1 including the step of decoding said information from said at least one information containing DNA sequence.

9. A method of writing information using DNA, comprising the steps of:

translating said information into information containing DNA sequence,

preselecting a basic DNA sequence,

synthesizing a DNA molecule of user-defined sequence that contains said information containing DNA sequence and said basic DNA sequence.

10. The method of writing information using DNA of claim 9 wherein said step of translating said information into an information containing DNA sequence comprises using a computer program to translate said information.

11. The method of writing information using DNA of claim 9 wherein said step of preselecting a basic DNA sequence comprises using a computer program to preselect basic DNA sequence.

12. The method of writing information using DNA of claim 9 wherein said steps of translating said information into an information containing DNA sequence and preselecting a basic DNA sequence comprise using computational techniques to break said sequences into fragments of defined size and said step of synthesizing a DNA molecule of user-defined sequence comprises assembling said fragments into said DNA molecule of user-defined sequence.

13. The method of writing information using DNA of claim 9 wherein pre-defined strings of DNA bases are located before and after said information containing DNA sequence in said DNA molecule of user-defined sequence.

14. The method of writing information using DNA of claim 9 wherein said steps of synthesizing a DNA molecule of user-defined sequence comprises providing a pre-defined, double-stranded, sequence of DNA with a single-stranded overhang, tethered said pre-defined, double-stranded, sequence of DNA with a single-stranded overhang, and lengthening said pre-defined, double-stranded, sequences of DNA by the addition of user-selected, single stranded DNA sequences.

15. The method of writing information using DNA of claim 9 wherein said steps of synthesizing a DNA molecule of user-defined sequence comprises providing a pre-defined, double-stranded, sequence of DNA with a single-stranded overhang, tethered said pre-defined, double-stranded, sequence of DNA with a single-stranded overhang with a bead, and lengthening said pre-defined, double-stranded, sequences of DNA by the addition of user-selected, single stranded DNA sequences.