Blood processing system

• US 20030229302A1
• Filed: 10/03/2002
• Published: 12/11/2003
• Est. Priority Date: 10/16/1998
• Status: Active Grant

• Current Assignee: Terumo Medical Corporation (Terumo Corporation)
• Original Assignee: Mission Medical, Inc. (Terumo Corporation)
• Inventors: Robinson, Thomas C., Hickman, Frank, Sahines, Thomas P., Fernandez, Robert K., DʼElia, Richard R.
• Granted Patent: US 6,817,984 B2
• Time in Patent Office: Days
• US Class Current: 604/4.01
• CPC Class Codes: A61M 1/02 Blood transfusion apparatus blood infusion by syringes A61M5/14
• CPC Class Codes: A61M 1/0218 with filters
• CPC Class Codes: A61M 1/024 Means for controlling the quantity of transfused blood, e.g. by weighing the container and automatic stopping of the transfusion after reaching a determined amount
• CPC Class Codes: A61M 1/025 Means for agitating or shaking blood containers A61M1/0245 takes precedence; shaking in general B01F31/00
• CPC Class Codes: A61M 1/0272 Apparatus for treatment of blood or blood constituents prior to or for conservation, e.g. freezing, drying or centrifuging
• CPC Class Codes: A61M 1/0281 Apparatus for treatment of blood or blood constituents prior to transfusion, e.g. washing, filtering or thawing
• CPC Class Codes: A61M 1/34 Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
• CPC Class Codes: A61M 1/342 Adding solutions to the blood, e.g. substitution solutions for preventing coagulation A61M1/3672
• CPC Class Codes: A61M 1/3458 having electrolytes not present in the dialysate
• CPC Class Codes: A61M 1/3489 by biological cells, e.g. bioreactor
• CPC Class Codes: A61M 1/3496 Plasmapheresis; Leucopheresis; Lymphopheresis A61M1/3472 takes precedence
• CPC Class Codes: A61M 1/36 Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
• CPC Class Codes: A61M 1/3603 in the same direction
• CPC Class Codes: A61M 1/362227 the interface providing means for actuating on functional elements of the cassette, e.g. plungers
• CPC Class Codes: A61M 1/36223 the cassette being adapted for heating or cooling the blood
• CPC Class Codes: A61M 1/36225 with blood pumping means or components thereof
• CPC Class Codes: A61M 1/362264 the filter being a blood filter
• CPC Class Codes: A61M 1/362265 Details of valves
• CPC Class Codes: A61M 1/362266 Means for adding solutions or substances to the blood
• CPC Class Codes: A61M 1/3633 Blood component filters, e.g. leukocyte filters
• CPC Class Codes: A61M 1/3672 : Means preventing coagulation
• CPC Class Codes: A61M 2205/125 : with incorporated filters
• CPC Class Codes: A61M 2205/126 : with incorporated membrane filters
• CPC Class Codes: A61M 2205/128 : with incorporated valves
• CPC Class Codes: A61M 2205/3306 : Optical measuring means
• CPC Class Codes: A61M 2205/3334 : Measuring or controlling the flow rate
• CPC Class Codes: A61M 2205/3368 : Temperature
• CPC Class Codes: A61M 2205/3606 : cooled
• CPC Class Codes: A61M 2205/3673 : thermo-electric, e.g. Peltier effect, thermocouples, semi-conductors
• CPC Class Codes: A61M 2205/50 : with microprocessors or computers
• CPC Class Codes: A61M 2230/207 : hematocrit

Abstract

A blood processing system (2), includes a housing (4), to which a user control panel is mounted, having an access opening (47) therein. A cassette assembly (22), mounted to the housing for movement between a use position covering the access opening and a cassette-replacement position, includes a cassette holder and cassette (26) removably mounted to the holder. The cassette includes in part by tubing aligned with a through-hole (45) in the cassette. A door (34) is mounted to the housing for movement between a latched position, capturing the cassette between the panel and the door, and a released position. Independently-driven roller assemblies (46, 54, 72) pass part-way through the access opening to capture first tubing portions (44A, 52A, 68A) between the roller tracks (100, 102, 104) and the roller assemblies for peristaltic pumping of fluid. A number of movable pinch elements (48, 80, 90, 96) are extendable through the front panel to selectively pinch the tubing against the door and thus seal the tubing.

Claims

1. An integrated blood processing system comprising a housing, a door mounted thereto and a disposable cassette, wherein:

the housing has a front side having operator-available controls exposed thereon and a signal processor enclosed in an interior thereof, the controls being connected in signal transferring relation to the signal processor, a plurality of roller pump roller assemblies mounted about a single axis and in close lateral relation to one another, the roller assemblies having circumferences which extend through a first opening adjacent to the housing front side, the first opening being of a size and shape sufficient to allow free passage of the roller assemblies circumferences, motivating means for independently motivating each of the roller assemblies to rotate about the single axis, the motivating means being in signal transmitting relation to the signal processor, a plurality of parallel plungers mounted to a corresponding plurality of independently controllable plunger motivating valves the plungers each having a contact end which can be extended by the respective valve, a second opening defined in the housing front side, the second opening being of a size and shape sufficient to allow free passage of the plungers, the plungers being spaced from one another, and the plungers being in signal transmitting relation to the signal processor;

the door being selectively positioned to expose or close a plurality of recessed roller backing portions, the roller backing portions being arcuate in shape and being separated by ridges from one another, the door, when closed, being latched against the housing front side;

the cassette having a body which is mountable between the door and the housing and resilient tubing mounted to the body, the body and the tubing mounted thereto being positioned between the door and the housing when the door is open and being firmly held in place between the door and the housing when the door is thereafter closed with the tubing then having a plurality of pumping portions thereof in contact with the circumferences of the respective rollers and in contact with the corresponding roller backing portions, the cassette having a plurality of flow shut-off portions positioned to shut off flow through the tubing on selected movement of the plunger contact ends into flow blocking relation thereto, whereby selective pumping is enabled at each pumping portion and whereby selective closure is provided at each flow shut off portion.