Directional needle injection drug delivery device and method of use
First Claim
1. A device for delivering a drug directly to a target site comprising:
- an elongate body surrounding an inner lumen and a needle lumen, whereby said inner lumen surrounds a retractable ultrasonic element;
a retractable needle housed within said needle lumen; and
an intravascular ultrasound (IVUS) system connected to a proximal end of said retractable ultrasonic element.
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Accused Products
Abstract
The invention relates to an apparatus and method for imaging and mapping various structures located at a target area within a patient'"'"'s lumen using conventional IVUS technology. The mapped images are used to accurately determine and control the location of the device within the lumen relative to the target area and/or target site. Once the drug delivery device is properly positioned within the lumen, additional ultrasonic images are generated and used to control the position and depth of penetration of a retractable needle of the device. Needle position can be precisely determined, both in relationship to the device as well as the target site for drug delivery. This allows accurate delivery of drug to the target site and, thus, enhanced treatment capabilities.
67 Citations
18 Claims
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1. A device for delivering a drug directly to a target site comprising:
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an elongate body surrounding an inner lumen and a needle lumen, whereby said inner lumen surrounds a retractable ultrasonic element;
a retractable needle housed within said needle lumen; and
an intravascular ultrasound (IVUS) system connected to a proximal end of said retractable ultrasonic element. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method of delivering a drug directly to a target site comprising:
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positioning a retractable ultrasonic element of a drug delivery device at said target area in a lumen;
generating a real-time image of said target area using said retractable ultrasonic element and an IVUS system;
determining a location of said target site from said image;
locating said drug delivery device at said target site, whereby a balloon of said drug delivery device is inflated to fixedly secure said device at said target site;
extending a retractable needle of said drug delivery device so that said needle penetrates said target site;
tracking said needle movement and depth of penetration into said target site using said retractable ultrasonic element and said IVUS system; and
extending said retractable needle a predetermined depth into said target site for dispensing drug directly to said target site. - View Dependent Claims (13, 14, 15, 16, 17, 18)
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Specification