Array assay devices and methods of using the same
First Claim
1. An array assay device, said device comprising:
- a substrate comprising at least one array sealed between a rigid bottom surface and a cover, wherein said rigid bottom surface and said cover are sealed to each other by a frangible seal.
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Abstract
Array assay devices and methods for using the same in array based assays are provided. The subject array assay devices are characterized by having a substrate having at least one array sealed between a rigid bottom surface and a cover, wherein the rigid bottom surface and the cover are sealed to each other by a frangible seal. The subject device may also include a sealing element for forming seals around a plurality of arrays to provide individual assay areas. The subject invention also includes methods for performing an array assay. In the subject methods, a subject array assay device is provided, a sample is contacted to the at least one array and an array assay is performed. The frangible seal may then be broken to expose the at least one array. The subject invention also includes kits which include the subject devices.
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Citations
40 Claims
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1. An array assay device, said device comprising:
a substrate comprising at least one array sealed between a rigid bottom surface and a cover, wherein said rigid bottom surface and said cover are sealed to each other by a frangible seal. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 38, 39, 40)
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17. An array assay device, said device comprising:
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(a) a substrate comprising at least one array; and
(b) a cover, wherein said substrate and said cover are sealed to each other by a frangible seal.
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18. A method for performing an array assay, said method comprising:
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(a) providing an array assay device comprising;
a substrate comprising at least one array sealed between a rigid bottom surface and a cover, wherein said rigid bottom surface and said cover are sealed to each other by a frangible seal;
(b) contacting said at least one array with a sample; and
(c) performing an array assay. - View Dependent Claims (19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33)
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34. A method of manufacturing an array assay device, said method comprising:
positioning a substrate having at least one array between a rigid bottom surface and a cover and frangibley sealing said rigid bottom surface and said cover to each other to seal said substrate having at least one array therebetween, whereby an array assay device is produced.
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35. A method of manufacturing an array assay device, said method comprising:
frangibley sealing a substrate having at least one array to a cover, whereby an array assay device is produced.
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36. A method for performing an array assay, said method comprising:
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(a) receiving an array assay device of claim I comprising said substrate having at least one array pre-packaged therein from a remote site;
(b) performing an array assay using said received array assay device;
(c) removing said pre-packaged substrate from said array assay device; and
(d) reading said at least one array to obtain a result. - View Dependent Claims (37)
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Specification