Optoelectronic and microfluidic integration for miniaturized spectroscopic devices
First Claim
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1. An apparatus for optical analysis, the apparatus comprising:
- a detector system;
a microfluidic system on the detector system;
wherein the apparatus is free from any lens system between the microfluidic system and the detector system.
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Abstract
Techniques for integrating optoelectronic system and microfluidic system. An apparatus for optical analysis includes a detector system and a microfluidic system on the detector system. The apparatus is free from any lens system between the microfluidic system and the detector system. Methods of making such an apparatus and using such an apparatus are also disclosed.
130 Citations
46 Claims
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1. An apparatus for optical analysis, the apparatus comprising:
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a detector system;
a microfluidic system on the detector system;
wherein the apparatus is free from any lens system between the microfluidic system and the detector system. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 28, 29)
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27. A method of making a system for optical analysis, the method comprising:
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providing a detector system on a substrate system with connection to an electrical contact system;
providing a microfluidic system on the detector system by replication molding;
providing a light source system coupled to the microfluidic system;
wherein the method is free from providing any lens system between the microfluidic system and the detector system. - View Dependent Claims (30, 31)
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32. A method of using an apparatus for absorption spectroscopy, the method comprising:
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loading test samples into a microfluidic system;
placing the microfluidic system on a detector system;
providing a light source system coupled to the microfluidic system;
sensing sample signals received at the detector system;
processing detector response signals;
determining an absorption spectrum using at least information associated with detector response signals;
wherein the method is free from providing any lens system between the microfluidic system and the detector system. - View Dependent Claims (33, 34)
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35. A method of using an apparatus for fluorescence spectroscopy, the method comprising:
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loading test samples into a microfluidic system;
placing the microfluidic system on a bottom filter system;
placing the bottom filter system on a detector system;
placing a light source system coupled to the microfluidic system;
sensing sample signals received at the detector system;
processing detector response signals;
determining an absorption spectrum using at least information associated with detector response signals;
wherein the method is free from providing any lens system between the microfluidic system and the detector system. - View Dependent Claims (36, 37)
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38. An apparatus comprising:
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a light source configured to emit light of at least one wavelength;
an photosensitive element including a pixel having a dimension; and
a sample holding element located between the light source and the photosensitive element, the sample holding element comprising a material substantially transparent to light of the wavelength, the sample holding element including a microfabricated recess configured to position a sample from the pixel at a distance of fifty-times the pixel dimension or less. - View Dependent Claims (39, 40)
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41. A method comprising:
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providing a photosensitive element including a pixel having a dimension;
providing a light source configured to emit light of at least one wavelength;
disposing between the light source and the photosensitive element, a sample within a recess of a sample holding element, at a distance of fifty-times the pixel dimension or less, the sample holding element substantially transparent to the light of the at least one wavelength; and
detecting with the photosensitive element an optical property of light from the sample. - View Dependent Claims (42, 43, 44, 45, 46)
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Specification