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Compositions of pegylated soluble tumor necrosis factor receptors and methods of preparing

  • US 20030236196A1
  • Filed: 06/12/2003
  • Published: 12/25/2003
  • Est. Priority Date: 06/20/2002
  • Status: Active Grant
First Claim
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1. A stable pharmaceutical formulation comprising at least 45 mg/ml PEGsTNF-R1, at least one tonicity modifier that is not NaCl, a surfactant and a buffer, wherein said pharmaceutical formulation is between pH 4.0 and 5.5 and wherein the viscosity is less than 400 cP.

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