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Implantable or insertable medical devices for controlled delivery of a therapeutic agent

  • US 20030236513A1
  • Filed: 06/19/2002
  • Published: 12/25/2003
  • Est. Priority Date: 06/19/2002
  • Status: Abandoned Application
First Claim
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1. A therapeutic-agent-releasing medical device comprising:

  • (a) an implantable or insertable medical device;

    (b) a release layer disposed over at least a portion of the implantable or insertable medical device, said release layer comprising (i) a first polymer comprising one or more polymer chains that form one or more polymer phase domains when the first polymer is in a pure solid-state form; and

    (ii) a second polymer comprising two or more polymer chains that form two or more phase domains when the second polymer is in a pure solid-state form, wherein at least one polymer chain in the second polymer is compatible with at least one polymer chain in the first polymer; and

    (c) a therapeutic agent, wherein said release layer regulates the rate of release of the therapeutic agent from the medical device upon implantation or insertion of the device into a patient.

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