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Alternate site gene therapy

  • US 20040002677A1
  • Filed: 12/11/2002
  • Published: 01/01/2004
  • Est. Priority Date: 12/11/2001
  • Status: Active Grant
First Claim
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1. A method for performing gene therapy on a selected section of a body lumen comprising:

  • placing within a selected section of the body lumen a catheter including one or more expandable members for occluding sections of the body lumen proximal and/or distal to the selected section;

    occluding sections of the body lumen proximal and/or distal to the selected section of the body lumen;

    delivering a gene therapy composition into the selected section of the body lumen;

    delivering ultrasound to the selected section of the body lumen for a period of time in the presence of the gene therapy composition under conditions where the ultrasound causes cavitation of cells in the selected section; and

    transplanting the selected section of the body lumen into another region of the body.

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