Carrier for chromatography, carrier for pre-treatment and kit for preparing the same

• US 20040007513A1
• Filed: 06/03/2003
• Published: 01/15/2004
• Est. Priority Date: 06/03/2002
• Status: Abandoned Application

• Current Assignee: Shinwa Chemical Industries, Ltd.
• Original Assignee: Shinwa Chemical Industries, Ltd.
• Inventors: Wada, Hiroo, Kanehara, Hideyuki
• Application Number:
  US10/452,307
• Publication Number:
  US 20040007513A1
• Time in Patent Office: Days
• US Class Current: 210/198.2
• CPC Class Codes: B01J 20/287 Non-polar phases; Reversed phases
• CPC Class Codes: B01J 20/3204 Inorganic carriers, supports or substrates
• CPC Class Codes: B01J 20/3208 Polymeric carriers, supports or substrates
• CPC Class Codes: B01J 20/3217 Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
• CPC Class Codes: B01J 20/3251 comprising at least two different types of heteroatoms selected from nitrogen, oxygen or sulphur
• CPC Class Codes: B01J 20/3265 with an organic functional group containing a metal, e.g. a metal affinity ligand
• CPC Class Codes: B01J 2220/54 Sorbents specially adapted for analytical or investigative chromatography
• CPC Class Codes: B01J 2220/86 Sorbents applied to inner surfaces of columns or capillaries
• CPC Class Codes: B82Y 30/00 Nanotechnology for materials or surface science, e.g. nanocomposites
• CPC Class Codes: Y10T 428/1393 Multilayer [continuous layer]

Abstract

A carrier for chromatography or a carrier for a pre-treatment comprises a carrier material consisting of a metal or a metal compound reactive with the sulfur-containing compound or a carrier material whose surface is coated with the foregoing metal or metal compound; and a sulfur-containing compound bonded to the surface of the foregoing carrier material and a kit for preparing a carrier for chromatography or a carrier for a pre-treatment comprises the foregoing carrier material; and a sulfur-containing compound. This carrier has a hydrophobic field established by groups such as octadecyl groups, which is never eliminated therefrom even under acidic and alkaline conditions; has thus a high separation power and a long service life; can easily be prepared within a short period of time; and therefore, the production cost thereof is quite low.

Claims

1. A carrier for chromatography or a carrier for a pre-treatment comprising a carrier material consisting of a metal or a metal compound reactive with a sulfur-containing compound or a carrier material whose surface is coated with the foregoing metal or metal compound wherein said sulfur-containing compound is bonded to the surface of the carrier material.

2. The carrier for chromatography or the carrier for a pre-treatment of claim 1 wherein the metal or metal compound is at least one member selected from the group consisting of gold, silver, copper, platinum, iron, mercury, silver oxide, copper oxide, gallium arsenide and indium phosphide.

3. The carrier for chromatography or the carrier for a pre-treatment of claim 1 or 2 wherein the carrier material is a porous or non-porous carrier material.

4. The carrier for chromatography or the carrier for a pre-treatment of claim 1 or 2 wherein the carrier material is at least one member selected from the group consisting of gold, silver, copper, platinum, iron, mercury, silver oxide, copper oxide, gallium arsenide and indium phosphide.

5. The carrier for chromatography or the carrier for a pre-treatment as set forth in any one of claims 1 to 4 wherein the carrier material is silica, glass, cellulose, ceramics, carbon or a cross-linkable polymeric compound.

6. The carrier for chromatography or the carrier for a pre-treatment as set forth in any one of claims 1 to 5 wherein the carrier material is a spherical, fiber-like or crushed carrier material or the internal surface of fine tubes.

7. The carrier for chromatography or the carrier for a pre-treatment as set forth in any one of claims 1 to 6 wherein the sulfur-containing compound is an alkane thiol compound having 4 to 40 carbon atoms.

8. The carrier for chromatography or the carrier for a pre-treatment as set forth in claim 7 wherein the thiol compound comprises octadecyl mercaptan.

9. The carrier for chromatography or the carrier for a pre-treatment as set forth in any one of claims 1 to 8 wherein the sulfur-containing compound comprises at least two kinds of sulfur-containing compounds.

10. A lit for preparing a carrier for chromatography or a carrier for a pre-treatment comprising a carrier material consisting of a metal or a metal compound reactive with a sulfur-containing compound or a carrier material whose surface is coated with the foregoing metal or metal compound;

and said sulfur-containing compound reactive with the metal or metal compound.