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Delivery of drug amines through an inhalation route

  • US 20040009128A1
  • Filed: 05/13/2003
  • Published: 01/15/2004
  • Est. Priority Date: 05/13/2002
  • Status: Active Grant
First Claim
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1. A method of selecting an amine drug salt suitable for use in forming a condensation aerosol, comprising a. dissolving or suspending an amine drug salt in a solvent, b. coating the suspended or dissolved amine drug salt on a substrate, c. heating the coated substrate to form a compound vapor, d. cooling the vapor to form aerosol particles, e. collecting the aerosol particles, f. analyzing the collected particles to determine the purity of the aerosol particles;

  • and g. selecting the amine drug based on a decomposition index less than 0. 15.

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