Porous and/or polycrystalline silicon orthopaedic implant

• US 20040010313A1
• Filed: 01/23/2003
• Published: 01/15/2004
• Est. Priority Date: 06/10/2000
• Status: Active Grant

• Current Assignee: pSiMedica Limited (EyePoint Pharmaceuticals, Inc.)
• Original Assignee: pSiMedica Limited (EyePoint Pharmaceuticals, Inc.)
• Inventors: Canham, Leigh T, Aston, Roger
• Granted Patent: US 7,186,267 B2
• Time in Patent Office: Days
• US Class Current: 623/17.11
• CPC Class Codes: A61B 17/064 Surgical staples, i.e. penetrating the tissue
• CPC Class Codes: A61B 17/68 Internal fixation devices , including fasteners and spinal fixators, even if a part thereof projects from the skin bone staples A61B17/0642
• CPC Class Codes: A61B 17/72 Intramedullary pins, nails or other devices A61B17/744 takes precedence
• CPC Class Codes: A61B 17/80 Cortical plates , i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
• CPC Class Codes: A61B 17/86 Pins or screws or threaded wires; nuts therefor A61B17/72 take precedence
• CPC Class Codes: A61B 17/866 Material or manufacture
• CPC Class Codes: A61B 2017/00004 (bio)absorbable, (bio)resorbable, resorptive for implantable prostheses A61F2210/0004
• CPC Class Codes: A61B 2017/0647 having one single leg, e.g. tacks
• CPC Class Codes: A61B 2017/0648 threaded, e.g. tacks with a screw thread
• CPC Class Codes: A61F 2/28 Bones joints A61F2/30
• CPC Class Codes: A61F 2/2875 Skull or cranium A61F2/2803 and A61F2/3099 take precedence
• CPC Class Codes: A61F 2/32 for the hip
• CPC Class Codes: A61F 2/446 having a circular or elliptical cross-section substantially parallel to the axis of the spine, e.g. cylinders or frustocones
• CPC Class Codes: A61F 2002/2817 Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
• CPC Class Codes: A61F 2002/30062 (bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
• CPC Class Codes: A61F 2002/30084 Materials having a crystalline structure
• CPC Class Codes: A61F 2002/30154 square
• CPC Class Codes: A61F 2002/30172 T-shaped
• CPC Class Codes: A61F 2002/30235 tubular, e.g. sleeves
• CPC Class Codes: A61F 2002/30677 Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
• CPC Class Codes: A61F 2002/30785 : parallel
• CPC Class Codes: A61F 2002/30789 : perpendicular with respect to each other
• CPC Class Codes: A61F 2002/30906 : shot- sand- or grit-blasted
• CPC Class Codes: A61F 2002/30925 : etched
• CPC Class Codes: A61F 2210/0004 : bioabsorbable
• CPC Class Codes: A61F 2230/0021 : square
• CPC Class Codes: A61F 2230/0052 : T-shaped
• CPC Class Codes: A61F 2230/0069 : cylindrical
• CPC Class Codes: A61F 2310/00353 : Bone cement, e.g. polymethylmethacrylate or PMMA
• CPC Class Codes: A61L 27/025 : Other specific inorganic materials not covered by A61L27/04 - A61L27/12
• CPC Class Codes: A61L 27/306 : Other specific inorganic materials not covered by A61L27/303 - A61L27/32
• CPC Class Codes: A61L 27/54 : Biologically active materials, e.g. therapeutic substances A61L27/227 takes precedence
• CPC Class Codes: A61L 27/56 : Porous materials, e.g. foams or sponges
• CPC Class Codes: A61L 31/028 : Other inorganic materials not covered by A61L31/022 - A61L31/026
• CPC Class Codes: A61L 31/088 : Other specific inorganic materials not covered by A61L31/084 or A61L31/086
• CPC Class Codes: A61L 31/146 : Porous materials, e.g. foams or sponges
• CPC Class Codes: A61L 31/16 : Biologically active materials, e.g. therapeutic substances A61L31/047 takes precedence

Abstract

The invention relates to orthopaedic implant materials and devices comprising porous and or polycrystalline silicon. Such materials and devices may be used in the treatment of one or more of the following conditions: hip fracture, arthrosis of the hip and knee, vertebral fracture, spinal fusion, long bone fracture, soft tissue repair, and osteoporosis.

Claims

1. An orthopaedic implant material comprising porous and or polycrystalline silicon.

2. An orthopaedic implant material according to claim 1 characterised in that the orthopaedic implant material has a structure and composition such that it is suitable for use in the treatment of one or more of the following conditions:

hip fracture, arthrosis of the hip and knee, vertebral fracture, spinal fusion, long bone fracture, soft tissue repair, and osteoporosis.

3. An orthopaedic implant material according to claim 1 characterised in that the porous and/or polycrystalline silicon is resorbable porous and/or polycrystalline silicon.

4. An orthopaedic implant material according to claim 1 characterised in that the orthopaedic implant material has a structure and composition such that it has an elastic modulus between 30 GPa and 1 GPa.

5. An orthopaedic implant material according to, claim 1 characterised in that the orthopaedic implant material further comprises a bone cement and/or polymer.

6. An orthopaedic implant material according to claim 1 characterised in that the orthopaedic material comprises one or more of:

a morphogenetic protein, an antimicrobial agent, a fluoride, a vitamin D metabolite, calcitonin, raloxifene, oestrogen, a hormone.

7. An orthopaedic implant material characterised in that the orthopaedic material comprises derivatised porous silicon having Si—

C and/or Si—

O—

C bonding.

8. An orthopaedic implant device formed, at least partly, from an orthopaedic implant material comprising porous and/or polycrystalline silicon

9. An orthopaedic implant device according to claim 8 characterised in that the device comprises a fixitor selected from one or more of:

a pin, a nail, a screw, a plate, a staple, a tack, an anchor, and a fixation block.

10. An orthopaedic implant device according to claim 8 characterised in that the device has a structure and composition such that it is suitable for the treatment of one or more of:

hip fracture, vertebral fracture, spinal damage, craniofacial damage, and long bone fracture.

11. An orthopaedic implant device according to claim 8 characterised in that the porous and/or polycrystalline material is arranged such that the surface of the orthopaedic device is at least partly formed from the porous and/or polycrystalline silicon.

12. An orthopaedic device according to claim 8 characterised in that the orthopaedic device further comprises animal and/or human bone.

13. An orthopaedic device according-to claim 12 characterised in that the device comprises a micromachined component.

14. A method of making an orthopaedic implant material comprising the steps:

taking a body of silicon or silicon containing compound, and forming the silicon or silicon containing compound into porous and/or polycrystalline silicon suitable for the treatment, and/or repair, and/or replacement of human or animal bone.

15. A method of making an orthopaedic implant device comprising the steps:

taking a body of porous and/or polycrystalline silicon, and forming at least part of a device, suitable for the treatment, and/or repair, and/or replacement of human or animal bone, from the porous and/or polycrystalline silicon.