Method for detecting displacements of the brain areas and the representation thereof on a display, said displacements caused by tumour formation

• US 20040013289A1
• Filed: 10/28/2002
• Published: 01/22/2004
• Est. Priority Date: 03/09/2000
• Status: Active Grant

• Current Assignee: Forschungsverbund Berlin E.V.
• Original Assignee: Forschungsverbund Berlin E.V.
• Inventors: Labudde, Dirk
• Granted Patent: US 7,043,068 B2
• Time in Patent Office: Days
• US Class Current: 382/128
• CPC Class Codes: A61B 90/36 Image-producing devices or illumination devices not otherwise provided for
• CPC Class Codes: G06T 2207/30016 Brain
• CPC Class Codes: G06T 7/60 Analysis of geometric attributes
• CPC Class Codes: G06T 7/73 using feature-based methods

Abstract

The invention relates to a method of detecting the displacement of individual brain areas and to the presentation thereof on a display for guaranteeing optimal planning of an operation, said displacements being caused by tumor formation. According to the invention a displacement vector is detected for each brain area which was situated at a defined location in the initial position where a tumor is located now. Said displacement vector defines the displacement of a brain area in the direction and the amount thereof, whereby said displacement is caused by tumor growth. Said vector is detected by means of two parameters (b and c) which can be derived from the size and the kind of the tumor. The displacement vectors are numerically calculated according to the formula u_r=cr+br⁻² after the two parameters have been detected. The image of the tumor as well as the detected displacements are subsequently inserted into a stereotactic atlas. The brain areas are displayed at the actual locations in the thus obtained image. Improved planning for carrying out operations can thus be guaranteed by means of said representation.

Claims

1. A method of determining displacements of brain areas as a result of tumor formation and of their presentation on an image screen utilizing stereotactic atlases

characterized by

determining by means of known physical correlations, particularly Hooke'"'"'s law, a displacement vector u(r) for each point of mass of a brain area (P₁, P₂, P₃, P_n) which in an initial state was located at a position described by a position vector (r₁, r₂, r₃, r_n) where the tumor (3) is now located, which displacement vector may be unambiguously defined by two parameters b, c, whereby the parameters b, c may be derived from the boundary conditions tumor size and tumor type and the displacement vectors u(r) are subsequently mathematically calculated and a new position vector (r₁₁, r₂₂, r₃₃, r_nn) is calculated for each point of mass of a brain area (P₁, P₂, P₃, P_n) as a result of the displacement, thereafter inserting the image of the tumor (3) as well as the determined displacements with the new position vectors (r₁₁, r₂₂, r₃₃, r_nn) which took place as a result of the tumor formation, into an anatomic atlas so that the brain areas characterized by the displaced points of mass (P₁₁, P₂₂, P₃₃, P_nn) are now displayed in the actual positions.

2. The method of claim 1,

characterized by the fact that

the parameters b, c are determined from an image of the tumor (3), in particular the size of the tumor and from an additional evaluation of the effects of the tumor formation by determining the maximum effect on the environment of the tumor (3).

3. The method of claim 1,

characterized by the fact that

the effect of the tumor formation on the environment of the tumor (3) which is characterized by the maximum effect, is determined from empirically determined correlations depending upon the type of tumor, the size of the tumor and further patient specific data.

4. The method of claim 3,

characterized by the fact that

the parameters b, c are determined by image recognition methods.

5. The method of claim 1,

characterized by the fact that

the displacement vectors u(r) for each point of mass of a brain area (P₁, P₂, P₃, P_n) are determined by the equation U_r=cr+br⁻

2.