Bioabsorbable plugs containing drugs
First Claim
1. A modular implantable drug delivery device adapted to be received within a shaped recess within an outer surface of an implantable prosthesis wherein the outer surface of the prosthesis has a surface contour, said device being operable for releasing a therapeutic agent into the body of an animal following implantation of the prosthesis within the body of the animal, the device comprising:
- (a) A solid module comprising a biodegradable polymer dimensioned to fit snugly within the shaped recess in the prosthesis; and
(b) A therapeutic agent that is released into the body of the animal during biodegration of said biodegradable polymer.
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Accused Products
Abstract
Bioabsorbable modular drug delivery devices having shapes and sizes adapted to be inserted within a mating receptacle on the surface of an implantable prosthesis are disclosed. The devices may be attached to one another to create custom drug delivery devices having controllable drug release characteristics that depend on the composition of individual modules comprising the device. The modules may be cylinders, disks, tiles or tubes comprised of a bioabsorbable polymer and a therapeutic agent. The therapeutic agent(s) may be homogeneously distributed throughout the polymeric body of the device or contained within a cavity within a module comprising the device, or both. The device(s) may be threaded or attached to a prosthesis by a biodegradable adhesive. The modular devices may also be formed into tapered plugs for insertion into a mating receptacle. In another embodiment, the drug delivery device may be inserted within a mesh bag that may be attached to a soft tissue as, for example, by sutures, for localized controlled dispensation of a therapeutic agent.
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Citations
9 Claims
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1. A modular implantable drug delivery device adapted to be received within a shaped recess within an outer surface of an implantable prosthesis wherein the outer surface of the prosthesis has a surface contour, said device being operable for releasing a therapeutic agent into the body of an animal following implantation of the prosthesis within the body of the animal, the device comprising:
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(a) A solid module comprising a biodegradable polymer dimensioned to fit snugly within the shaped recess in the prosthesis; and
(b) A therapeutic agent that is released into the body of the animal during biodegration of said biodegradable polymer. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. An implantable modular drug delivery device comprising:
- (a) a mesh container; and
(b) at least one solid module comprising a biodegradable polymer and a therapeutic agent contained within said mesh container.
- (a) a mesh container; and
Specification