Single dose delivery device

• US 20040015128A1
• Filed: 05/12/2003
• Published: 01/22/2004
• Est. Priority Date: 02/16/1999
• Status: Active Grant

• Current Assignee: Michael A. Taylor
• Original Assignee: Michael A. Taylor
• Inventors: Taylor, Michael A.
• Granted Patent: US 6,932,791 B2
• Time in Patent Office: Days
• US Class Current: 604/92
• CPC Class Codes: A61M 2005/3142 Modular constructions, e.g. supplied in separate pieces to be assembled by end-user
• CPC Class Codes: A61M 5/282 by compression of deformable ampoule or carpule wall
• CPC Class Codes: A61M 5/284 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/288 by piercing without internal pressure increase A61M5/283 takes precedence
• CPC Class Codes: A61M 5/31531 Microsyringes, e.g. having piston bore diameter close or equal to needle shaft diameter
• CPC Class Codes: A61M 5/3294 comprising means for injection of two or more media, e.g. by mixing

Abstract

A microinjection system comprises a device for housing dried forms of medical reagents, such as vaccines, hormones, etc. in single doses. Within a single chamber, a dry reagent bed is provided adjacent a compression component that keeps the bed compacted. In operation, diluent flows through the chamber to carry the reagent out of the chamber in fluid form. In the illustrated embodiments, the fluid carrying reagent is directly delivered from the chamber via a needle. Integral or connectable diluent delivery devices are disclosed for providing an appropriate volume of diluent to the reagent chamber. Unstable formulations of drugs, for example, can be safely stored in dry form. When injection is needed, the drug can be delivered almost instantly in fluid form simply by releasing diluent through the chamber, where the reagent bed is dissolved or suspended while the remaining reagent is continually compacted. The resultant fluid contains a single dose of the reagent and is delivered directly to a patient, desirably without measurement of the fluid form.

Claims

1. A system for delivering single dose units of medical reagents in fluid form, comprising:

a chamber including a dry reagent bed having a mass of no more than about 1.0 g;

a compression component in the chamber for exerting pressure upon the reagent bed; and

a delivery mechanism integrally connected and downstream of the chamber for delivering the reagent in a liquid.