Triazole derivatives and pharmaceutical compositions comprising them
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Abstract
The present invention relates to compounds of formula (I) and their pharmaccutically acceptable salts, solvates, hydrates and polymorphs. These compounds are powerful and selective CCK1 receptor agonists.
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14 Claims
- 1. Compound of formula:
-
3. Salts of the 3-aminotriazole derivative of the formula (I) and of its polymorphic and solvate (pseudopolymorphic) forms, given with ethanolamine of the formula (A):
- HO—
(CH2)2—
NH2, or diethanolamine of the formula (B);
HO—
(CH2)2—
NH—
(CH2)2—
OH, or diethylamine of the formula (C);
- HO—
-
4. 3-[2-[[[1-(2-cyclohexylethyl)-5-(2,5-dimethoxy-4-methylphenyl)-1H-1,2,4-triazol-3-yl]amino]carbonyl]-6-methoxy-4,5-dimethyl-1H-indol-1-yl]propionic acid ethanolamine salt.
Specification