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Separation system, components of a separation system and methods of making and using them

  • US 20040020855A1
  • Filed: 06/25/2003
  • Published: 02/05/2004
  • Est. Priority Date: 06/26/2002
  • Status: Active Grant
First Claim
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1. A chromatographic system comprising:

  • a pumping system;

    a column and detector array;

    a collector system; and

    a controller;

    said column and detector array including a plurality of columns;

    each of said columns containing a corresponding one of a plurality of size-compensated polymeric plugs;

    each of said size-compensated polymeric plugs having the same characteristics, whereby said columns separate sample in a similar manner;

    a source of solvent;

    said pumping system being arrange to supply solvent from the source of solvent to the column and detector array under the control of the controller wherein effluent flows into the collector system from the column and detector array under the control of the controller;

    said controller being connected to receive signals from detectors in the column and detector array indicating bands of solute and to activate the fraction collector accordingly.

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