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System and method for optimizing drug theraphy for the treatment of diseases

  • US 20040023211A1
  • Filed: 03/12/2003
  • Published: 02/05/2004
  • Est. Priority Date: 09/15/2000
  • Status: Abandoned Application
First Claim
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1. A method of measuring the efficacy of at least one therapeutic agent comprising:

  • determining an actual concentration of said at least one therapeutic agent;

    determining a pharmacologic exposure using a population pharmacokinetic model for said at least one therapeutic agent;

    determining resistance of an etiologic agent towards said at least one therapeutic agent;

    determining an inhibitory quotient for said at least one therapeutic agent based on said pharmacologic exposure and said resistance, and using said inhibitory quotient to determine efficacy of said at least one therapeutic agent.

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