Implantable biosensor from stratified nanostructured membranes
First Claim
1. A biosensor apparatus comprising at least one LBL layer and at least one responsive layer, where the responsive layer undergoes a change in a detectable property in response to a change in a target physical and/or chemical characteristic of a biological system and where the LBL layer improves detection of the detectable property.
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Accused Products
Abstract
A new class of biosensors and methods for making and using same are disclosed. The biosensors are multi-layered membrane composites, where at least one layer is prepared by the layer-by-layer process and at least one layer is responsive to changes is a property of a biological system such as changes in the concentration of an atom, ion, molecule or molecular assembly. Because the biosensors are multi-layered, a single biosensor is capable monitor a number of different properties of a biological system simultaneously. The biosensors are monitored by systems that impinge an excitation waveform on the biosensors and analyze a reflected and/or a transmitted resultant waveform. Additionally, the biosensors can be associated with field activated electronic components so that implantable, self-contained analytical devices can be constructed and monitored by field generators, where data is transmitted to an analyzer after field activation.
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Citations
20 Claims
- 1. A biosensor apparatus comprising at least one LBL layer and at least one responsive layer, where the responsive layer undergoes a change in a detectable property in response to a change in a target physical and/or chemical characteristic of a biological system and where the LBL layer improves detection of the detectable property.
- 8. A biosensor/detector apparatus comprising an excitation electronic component, a biosensor component including at least one LBL layer and at least one responsive layer, and a detection electronic component, where the excitation electronic component generates an input waveform that propagates through the biosensor producing an output waveform which enters the detector component and the responsive layer undergoes a change in a detectable property in response to a change in a physical and/or chemical characteristic of a biological system and where the LBL layer improves detection of the detectable property
Specification