Methods for genomic analysis
First Claim
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1. A business method comprising:
- identifying disease related loci by comparing frequencies of SNP haplotype patterns from essentially coding regions of individuals in a control group with frequencies of SNP haplotype patterns from essentially coding regions of individuals in a disease group, wherein differences in said frequencies indicate locations of disease-related genetic loci;
using said disease related loci in a discovery process; and
collaboratively or independently, marketing products from said discovery process.
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Abstract
The present invention relates to business methods for discovery of therapeutic and diagnostic products by identifying variations that occur in the human genome, relating these variations to one another, and, ultimately, relating these variations to the genetic bases of phenotype such as disease resistance, disease susceptibility or drug response.
27 Citations
15 Claims
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1. A business method comprising:
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identifying disease related loci by comparing frequencies of SNP haplotype patterns from essentially coding regions of individuals in a control group with frequencies of SNP haplotype patterns from essentially coding regions of individuals in a disease group, wherein differences in said frequencies indicate locations of disease-related genetic loci;
using said disease related loci in a discovery process; and
collaboratively or independently, marketing products from said discovery process. - View Dependent Claims (2, 3, 4)
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5. A business method comprising:
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a. making an association between SNP haplotype patterns from coding regions of a genome and a phenotypic trait of interest by i. building a baseline of SNP haplotype patterns from regions consisting essentially of coding regions of a genome;
ii. pooling genomic DNA from a population having a common phenotypic trait of interest;
iii. identifying said SNP haplotype patterns that are associated with said phenotypic trait of interest;
b. using said association in a discovery process; and
c. collaboratively or independently, marketing products from said discovery process. - View Dependent Claims (6, 7, 8, 10, 11, 12, 13, 14, 15)
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9. The method of claim I or 5 wherein the step of collaboratively or independently marketing products comprises receiving funds from a partner for making the association between the SNP patterns and the phenotypic trait.
Specification