Sensor arrays for detecting analytes in fluids
First Claim
1. A sensor array for detecting an analyte in a fluid for use in conjunction with an electrical measuring apparatus, said array comprising at least first and second chemical sensors each comprising:
- at least first and second conductive leads suitable for electrical connection to the electrical measuring apparatus and electrically coupled to a chemically sensitive resistor comprising a plurality of alternating nonconductive regions comprising a nonconductive organic polymer and conductive regions comprising a conductive material compositionally different than said nonconductive organic polymer, said resistor providing an electrical path between said conductive leads and through said regions, a first electrical resistance between said conductive leads when said resistor is contacted with a first fluid comprising a chemical analyte at a first concentration, and a second electrical resistance between said conductive leads when said resistor is contacted with a second fluid comprising said chemical analyte at a second different concentration, the difference between said first electrical resistance and said second electrical resistance of said first chemical sensor being different from the difference between said first electrical resistance and said second electrical resistance of said second chemical sensor.
1 Assignment
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Accused Products
Abstract
Chemical sensors for detecting analytes in fluids comprise first and second conductive elements (e.g. electrical leads) electrically coupled to and separated by a chemically sensitive resistor which provides an electrical path between the conductive elements. The resistor comprises a plurality of alternating nonconductive regions (comprising a nonconductive organic polymer) and conductive regions (comprising a conductive material) transverse to the electrical path. The resistor provides a difference in resistance between the conductive elements when contacted with a fluid comprising a chemical analyte at a first concentration, than when contacted with a fluid comprising the chemical analyte at a second different concentration. Arrays of such sensors are constructed with at least two sensors having different chemically sensitive resistors providing dissimilar such differences in resistance. Variability in chemical sensitivity from sensor to sensor is provided by qualitatively or quantitatively varying the composition of the conductive and/or nonconductive regions. An electronic nose for detecting an analyte in a fluid may be constructed by using such arrays in conjunction with an electrical measuring device electrically connected to the conductive elements of each sensor.
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Citations
13 Claims
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1. A sensor array for detecting an analyte in a fluid for use in conjunction with an electrical measuring apparatus, said array comprising at least first and second chemical sensors each comprising:
at least first and second conductive leads suitable for electrical connection to the electrical measuring apparatus and electrically coupled to a chemically sensitive resistor comprising a plurality of alternating nonconductive regions comprising a nonconductive organic polymer and conductive regions comprising a conductive material compositionally different than said nonconductive organic polymer, said resistor providing an electrical path between said conductive leads and through said regions, a first electrical resistance between said conductive leads when said resistor is contacted with a first fluid comprising a chemical analyte at a first concentration, and a second electrical resistance between said conductive leads when said resistor is contacted with a second fluid comprising said chemical analyte at a second different concentration, the difference between said first electrical resistance and said second electrical resistance of said first chemical sensor being different from the difference between said first electrical resistance and said second electrical resistance of said second chemical sensor. - View Dependent Claims (2, 3, 4)
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5. An system for detecting an analyte in a fluid, said system comprising:
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at least first and second chemical sensors each comprising at least first and second conductive leads electrically coupled to a chemically sensitive resistor comprising a plurality of alternating nonconductive regions comprising a nonconductive organic polymer and conductive regions comprising a conductive material compositionally different than said nonconductive organic polymer, said resistor providing an electrical path between said conductive leads and through said regions, a first electrical resistance between said conductive leads when said resistor is contacted with a first fluid comprising a chemical analyte at a first concentration and a second different electrical resistance when said resistor is contacted with a second fluid comprising said chemical analyte at a second different concentration, the difference between said first electrical resistance and said second electrical resistance of said first chemical sensor being different from the difference between said first electrical resistance and said second electrical resistance of said second chemical sensor;
an electrical measuring device electrically connected to at least one of said conductive leads; and
a computer comprisng a resident algorithm;
said electrical measuring device being capable of detecting said first and said second electrical resistances in each said sensor and said computer capable of assembling said resistances into a sensor array response profile. - View Dependent Claims (6, 7, 8)
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9. A method for detecting the presence of an analyte in a fluid, said method comprising:
resistively sensing the presence of an analyte in a fluid with a chemical sensor comprising first and second conductive leads electrically coupled to a chemically sensitive resistor comprising a plurality of alternating nonconductive regions comprising a nonconductive organic polymer and conductive regions comprising a conductive material compositionally different than said nonconductive organic polymer, said resistor providing an electrical path between said conductive leads and through said regions, a first resistance between said conductive elements when said resistor is contacted with a first fluid comprising a chemical analyte at a first concentration and a second different resistance when said resistor is contacted with a second fluid comprising said chemical analyte at a second different concentration. - View Dependent Claims (10, 11, 12, 13)
Specification