Spectroscopy illuminator with improved delivery efficiency for high optical density and reduced thermal load
First Claim
1. A method of monitoring tissue oxygenation involving:
- (a) placing an oximeter probe on, in or near a living tissue at mucosal or subsurface tissue site;
(b) illuminating the tissue with a broadband visible illumination;
(c) monitoring light returning from the subsurface or mucosal tissue cite, said light comprising at least one set of visible wavelengths from 400 to 700 nm; and
(d) determining the tissue hemoglobin oxygenation index saturation.
8 Assignments
0 Petitions
Accused Products
Abstract
An improved illuminator for generating broadband light, and for delivering the light to a sample with an improved delivery efficiency, for higher optical density and/or reduced thermal transfer, than achieved with conventional halogen bulb sources. The illuminator enables spectroscopic analysis in thermally-sensitive or spatially-constrained environments. A phosphor-coated broadband white LED and integrated collimating optics produces a continuous, collimated broadband light beam from 400 nm to 700 nm, which is then transmitted through space to a sample region, such as a living tissue in vivo. A method and system for measuring oxigeneration of mucosal or subsurface tissue is also described.
69 Citations
10 Claims
-
1. A method of monitoring tissue oxygenation involving:
-
(a) placing an oximeter probe on, in or near a living tissue at mucosal or subsurface tissue site;
(b) illuminating the tissue with a broadband visible illumination;
(c) monitoring light returning from the subsurface or mucosal tissue cite, said light comprising at least one set of visible wavelengths from 400 to 700 nm; and
(d) determining the tissue hemoglobin oxygenation index saturation. - View Dependent Claims (7)
-
-
2. The method of claim 25 wherein said tissue site is selected from the list of tissues consisting of oropharynx, nasopharynx, esophagus, stomach, duodenum, ileum, colon, or other gastrointestinal mucosal or superficial tissue.
-
3. A method of monitoring tissue oxygenation involving:
-
(a) illuminating the tissue with a broadband visible illumination having shallow-penetrating wavelengths shorter than 600 nm;
(b) monitoring shallow-penetrating visible light returning from the mucosal or subsurface tissue site; and
(c) determining a tissue hemoglobin oxygenation index based upon the returning visible light. - View Dependent Claims (4, 5, 6)
-
-
8. A visible wavelength optical spectroscopy oximeter system comprising:
-
(a) a broadband, low-thermal-transfer visible illumination source for illuminating a target region;
(b) an optical collector for collecting light scattered from said target region and for transmitting a collected signal to a spectroscopic monitor; and
(c). spectroscopic monitoring means for receiving and analyzing collected broadband visible light as a function of wavelength, said analysis substantially reliant upon received light with a wavelength below 600 nm so as to achieve a shallow, subsurface depth of penetration, and for determining an oxygen saturation index of hemoglobin in the target region based upon said monitored shallow penetrating visible light. - View Dependent Claims (9, 10)
-
Specification