Method of treating and preventing hyperparathyroidism with active vitamin D analogs
First Claim
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1. A method of lowering or maintaining lowered serum parathyroid hormone level in human patients suffering from hyperparathyroidism secondary to chronic kidney disease, comprising administering to the patients an effective amount of a vitamin D analog to lower and maintain lowered serum parathyroid hormone levels, the analog comprising a compound of formula (I):
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Abstract
This invention relates to a method for treating or preventing hyperthyroidism secondary to chronic kidney disease by administering a sufficient amount of an active vitamin D analog utilizing a variety of effective treatment protocols.
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34 Claims
- 1. A method of lowering or maintaining lowered serum parathyroid hormone level in human patients suffering from hyperparathyroidism secondary to chronic kidney disease, comprising administering to the patients an effective amount of a vitamin D analog to lower and maintain lowered serum parathyroid hormone levels, the analog comprising a compound of formula (I):
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25. A method of treating hyperparathyroidism associated with chronic kidney disease, comprising administering to a subject suffering therefrom an amount of an active vitamin D analog which includes at least one of 1α
- -OH-vitamin D2;
1α
,24-(OH)2-vitamin D2; and
1α
,24(S)-(OH)2-vitamin D2 sufficient to lower or maintain lowered blood parathyroid hormone (PTH) levels. - View Dependent Claims (26, 27, 28)
- -OH-vitamin D2;
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29. A method of treating hyperparathyroidism secondary to chronic kidney disease, comprising administering to a patient suffering therefrom an amount of 1α
- -OH-vitamin D2 sufficient to lower or maintain lowered blood parathyroid hormone (PTH) levels.
- View Dependent Claims (30, 31, 32, 33, 34)
Specification