System and method for treating abnormal ventricular activation-recovery time
First Claim
1. An implantable cardiac stimulation device, comprising:
- a physiological sensor that detects a physiologic parameter associated with a diurnal state of the patient;
a QT measuring circuit that measures a QT interval based on at least one of an evoked cardiac event or an intrinsic cardiac event;
a pulse generator that delivers pacing pulses to at least one chamber of the patient'"'"'s heart at an adjustable pacing rate; and
a control circuit connected to the physiological sensor, pulse generator, and to the QT measuring circuit, wherein the control circuit is operative to process the physiological parameter to determine the diurnal state, and that is operative to determine when the measured QT interval is abnormally long for the diurnal state, and that is operative to adjust the pacing rate to shorten the QT interval to within a normal range.
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Accused Products
Abstract
An implantable cardiac stimulation device provides long QT interval therapy for preventing abnormal ventricular activation-recovery time and ultimately ventricular arrhythmias. The device includes a sensing circuit that senses intracardiac activity of a heart and that generates electrical signals representing electrical activity of the heart. The device includes a physiologic sensor, such as body motion, or other diurnally varying sensor that reliably detects a diurnal state of the patient (i.e., not the QT interval itself). The device further includes a measuring circuit that measures a QT interval of the electrical signals, a control circuit that determines whether the QT interval is appropriate for the diurnal state, and a pulse generator that delivers pacing pulses to at least one chamber of the heart at a pacing rate when the QT Interval is pathologically too long. Furthermore, the pacing rate control circuit varies the pacing rate of the pulse generator responsive to the measured QT interval according to the measured diurnal state.
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Citations
64 Claims
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1. An implantable cardiac stimulation device, comprising:
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a physiological sensor that detects a physiologic parameter associated with a diurnal state of the patient;
a QT measuring circuit that measures a QT interval based on at least one of an evoked cardiac event or an intrinsic cardiac event;
a pulse generator that delivers pacing pulses to at least one chamber of the patient'"'"'s heart at an adjustable pacing rate; and
a control circuit connected to the physiological sensor, pulse generator, and to the QT measuring circuit, wherein the control circuit is operative to process the physiological parameter to determine the diurnal state, and that is operative to determine when the measured QT interval is abnormally long for the diurnal state, and that is operative to adjust the pacing rate to shorten the QT interval to within a normal range. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48)
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49. An implantable cardiac stimulation device for treating abnormal ventricular activation-recovery time, comprising:
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means for detecting a patient'"'"'s diurnal state including at least a sleep and an awake state;
means for measuring QT intervals based on at least one of an evoked cardiac event or an intrinsic cardiac event;
pulse generating means for generating pacing pulses to control a pacing interval of the pacing pulses; and
control means, in response to the measuring means, for adjusting the pacing interval by an amount that sufficiently shortens the QT interval to maintain the QT interval to within a normal range for the detected diurnal state. - View Dependent Claims (50, 51, 52, 53, 54, 55, 56)
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57. A method for treating abnormal ventricular activation-recovery time using an implantable cardiac stimulation device, comprising:
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detecting a diurnally varying parameter of the patient;
correlating the patient'"'"'s diurnally varying parameter to an activity state including at least a sleep and an awake state;
measuring QT intervals based on at least one of an evoked cardiac event or an intrinsic cardiac event during the sleep and awake states;
generating pacing pulses to control a pacing interval of the pacing pulses; and
adjusting the pacing interval by an amount that sufficiently shortens the QT interval to maintain the QT interval to within a normal range for the detected activity state. - View Dependent Claims (58, 59, 60, 61, 62, 63, 64)
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Specification