Indicators for monitoring the technique of transcutaneous immunization
First Claim
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1. A transcutaneous immunization system, for immunizing a subject comprising:
- a transcutaneous immunization formulation;
said immunization formulation comprising at least one antigen, and a marking formulation;
said marking formulation comprising at least one chemical indicator, the presence of said indicator serving to provide a readily discernable indication of the use of said immunization formulation, wherein said transcutaneous immunization system provides an antigen specific immune response in the subject following the application of said system to intact skin of said subject.
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Abstract
Transcutaneous immunization system delivers antigen to immune cells through topical application, and induces an antigen-specific immune response in an animal or human. The improvement involve a system for marking the successful delivery of the immunization using indicators or using marking systems to allow better application of the patch to a prepared skin surface.
7 Citations
25 Claims
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1. A transcutaneous immunization system, for immunizing a subject comprising:
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a transcutaneous immunization formulation;
said immunization formulation comprising at least one antigen, anda marking formulation;
said marking formulation comprising at least one chemical indicator, the presence of said indicator serving to provide a readily discernable indication of the use of said immunization formulation,wherein said transcutaneous immunization system provides an antigen specific immune response in the subject following the application of said system to intact skin of said subject. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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21. A method for eliciting an immune response from a subject by the application of an immunization system, said method comprising:
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applying an immunization formulation to at least one application site on the intact skin of a subject, said immunization formulation comprising at least one antigen; and
applying a marking formulation to said at least one application site, wherein said method provides an antigen specific immune response in the subject following the application of said system to intact skin of said subject. - View Dependent Claims (22, 23, 24, 25)
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Specification