Composition for an injectable bone mineral substitute material
First Claim
1. An injectable composition for a bone mineral substitute material with the capability of being hardened in a body fluid in vivo, which comprises a dry powder mixed with an aqueous liquid, characterized in that said dry powder comprises a first reaction component comprising a calcium sulphate hemihydrate with the capability of being hardened to calcium sulphate dihydrate when reacting with said aqueous liquid;
- a second reaction component, which comprises a calcium phosphate with the capability of being hardened to a calcium phosphate cement when reacting with said aqueous liquid; and
at least one accelerator for the reaction of said first and/or second reaction component with said aqueous liquid.
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Abstract
The invention refers to an injectable composition for a bone mineral substitute material, which comprises a dry powder mixed with an aqueous liquid. The powder comprsises a first reaction component comprising a calcium sulphate hemihydrate with the capability of being hardened to calcium sulphate dihydrate when reacting with said aqueous liquid; a second reaction component, which comprise a calcium phosphate with the capability of being hardened to a calcium phosphate cement when reacting with said aqueous liquid; and at least one accelerator for the reaction of said fist and/or second reaction component with said aqueous liquid. A method of producing an injectable bone mineral substitute material is also provided, wherein the composition is mixed in a closed mixing an d delivery system for delivery.
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Citations
33 Claims
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1. An injectable composition for a bone mineral substitute material with the capability of being hardened in a body fluid in vivo, which comprises a dry powder mixed with an aqueous liquid, characterized in that said dry powder comprises
a first reaction component comprising a calcium sulphate hemihydrate with the capability of being hardened to calcium sulphate dihydrate when reacting with said aqueous liquid; -
a second reaction component, which comprises a calcium phosphate with the capability of being hardened to a calcium phosphate cement when reacting with said aqueous liquid; and
at least one accelerator for the reaction of said first and/or second reaction component with said aqueous liquid. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33)
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Specification