Solid dose delivery vehicle and methods of making same
First Claim
1. A method for making an amorphous or non-crystalline solid dose delivery vehicle, the vehicle comprising a hydrophobic material and a polyol, said method comprising the steps of dissolving or suspending the polyol and hydrophobic material in an organic/aqueous solvent, removing the solvent and forming the vehicle.
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Abstract
The present invention encompasses a solid dose delivery vehicle for ballistic administration of a bioactive material to subcutaneous and intradermal tissue, the delivery vehicle being sized and shaped for penetrating the epidermis. The delivery vehicle further comprises a stabilizing polyol glass loaded with the bioactive material and capable of releasing the bioactive material in situ. The present invention further includes methods of making and using the solid dose delivery vehicle of the invention.
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Citations
12 Claims
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1. A method for making an amorphous or non-crystalline solid dose delivery vehicle, the vehicle comprising a hydrophobic material and a polyol,
said method comprising the steps of dissolving or suspending the polyol and hydrophobic material in an organic/aqueous solvent, removing the solvent and forming the vehicle.
Specification