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Modified peptides as therapeutic agents

  • US 20040053845A1
  • Filed: 07/31/2003
  • Published: 03/18/2004
  • Est. Priority Date: 10/23/1998
  • Status: Active Grant
First Claim
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1. A composition of matter of the formula (X1)a

  • F1

    (X2)b and multimers thereof, wherein;

    F1 is an Fc domain;

    X1 and X2 are each independently selected from -(L1)c-P1, -(L1)c-P1-(L1)c-P1-(L2)d-P2-(L3)e-P3-(L4)f-P4 P1, P2, P3, and P4 are each independently sequences of pharmacologically active peptides;

    L1, L2, L3, and L4 are each independently linkers; and

    a, b, c, d, e, and f are each independently 0 or 1, provided that at least one of a and b is 1.

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