Novel method and device for treatment of exercise induced pulmonary hemorrhage in horses
First Claim
1. A method for the treatment of exercise induced pulmonary hemorrhage (EIPH) in an equine, comprising administering to the equine a therapeutic amount of a composition comprised of sildenafil citrate or a pharmaceutically acceptable derivative thereof.
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Accused Products
Abstract
A device and method are provided for convenient, patient compliant inhalation therapy of equine species. The device can be used to deliver any drug or other pharmaceutical agent which can be adapted for inhalation directly into the nasal passages of a horse and thereby provide inhalation therapy with minimal discomfort. The device can be used to treat any of a number of conditions including, EIPH, infections and allergies, e.g., asthma or heaves. In one embodiment, the invention provides a method for the treatment or prevention of EIPH, utilizing a composition adapted for inhalant therapy comprised of sildenafil citrate alone or in combination other agents.
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Citations
46 Claims
- 1. A method for the treatment of exercise induced pulmonary hemorrhage (EIPH) in an equine, comprising administering to the equine a therapeutic amount of a composition comprised of sildenafil citrate or a pharmaceutically acceptable derivative thereof.
- 20. A method for the prevention of exercise induced pulmonary hemorrhage (EIPH) in an equine, comprising administering to the equine a prophylactic amount of a composition comprised of sildenafil citrate or a pharmaceutically acceptable derivative thereof.
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39. A device for removable attachment to the head of an equine that is adapted to provide inhalation therapy of a preselected agent to the subject equine, the device comprising:
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Bilateral elongated delivery tubes, each tube having a proximal end, a distal end and a body there between defining a longitudinal axis, the bilateral elongated delivery tubes being positioned relative to one another such that the body of each tube is substantially parallel along the longitudinal axis;
An inhalator manifold having a proximal end and a distal end;
the distal end of the inhalator manifold being in fluid connection with the proximal ends of the elongated delivery tubes and in fluid communication with a remote drug supply means at the proximal end of the inhalator manifold; and
Attachment means for removable attachment of the device to the head of the subject equine such that the longitudinal axis of each elongated delivery tube is held in a preselected position that is substantially parallel to the bridge of the nose of the subject equine'"'"'s forehead with the distal ends of the bilateral elongated delivery tubes held adjacent the external openings of the nostrils of the subject equine. - View Dependent Claims (40, 41, 42, 43, 44, 45, 46)
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Specification