Dynamic color imaging method and system

• US 20040057608A1
• Filed: 11/24/2003
• Published: 03/25/2004
• Est. Priority Date: 10/24/1997
• Status: Active Grant

• Current Assignee: Ultra Touch Corporation
• Original Assignee: Ultra Touch Corporation
• Inventors: Souluer, Farid
• Granted Patent: US 6,868,171 B2
• Time in Patent Office: Days
• US Class Current: 382/128
• CPC Class Codes: A61B 5/0053 by applying pressure, e.g. compression, indentation, palpation, grasping, gauging
• CPC Class Codes: A61B 5/0064 Body surface scanning
• CPC Class Codes: A61B 5/0091 for mammography
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/0537 Measuring body composition by impedance, e.g. tissue hydration or fat content
• CPC Class Codes: A61B 5/4312 Breast evaluation or disorder diagnosis A61B5/0091 takes precedence
• CPC Class Codes: A61B 5/442 Evaluating skin mechanical properties, e.g. elasticity, hardness, texture, wrinkle assessment
• CPC Class Codes: A61B 5/4872 Body fat
• CPC Class Codes: A61B 5/6843 Monitoring or controlling sensor contact pressure
• CPC Class Codes: A61B 5/704 Tables

Abstract

The present invention provides color images of tissue characteristics for determining the existence can location of tissue anomalies. An image of tissue is received, divided into pre-determined portions and accompanied by X and Y coordinates describeing the tissue relative to a subject. Characteristic data of the tissue is received for each portion of the image and is displayed by color according to characteristic data value. Characteristic data can also be determined and displayed for each portion of the image over multiple levels. Multiple images, one for each level, can be scrolled through for a common set of X and Y coordinates of tissue. Or, a three dimensional image is created, having respective levels displayed simultaneously, with color representative of the tissue characteristics for the entire depth of the tissue investigated. Additionally, color images are developed that compare and display differences in characteristic data of tissue over time.

Claims

1. A method for imaging tissue characteristics, comprising the steps of:

a. developing an image of tissue, the image divided into pre-determined portions and accompanied by data describing a first and a second coordinate of the tissue relative to a subject body for each portion of the image;

b. receiving characteristic data of the tissue for each portion of the image, each portion of the image having a first and a second coordinate relative to the image;

c. associating a color to the characteristic data for each portion of the image; and

d. displaying the color for each portion of the image, whereby differing colors displayed over the image assist in determining the existence of tissue anomalies in the subject body.

2. The method of claim 1, wherein each portion of the image is a pixel.

3. The method of claim 1, wherein the characteristic data is density.

4. The method of claim 1, further including the step of calculating and recording a size for tissue of predetermined characteristic value.

5. The method of claim 1, wherein the image of tissue is received from a camera.

6. The method of claim 1, wherein the data describing the first and the second coordinate of the tissue relative to a subject body is received from a camera.

7. The method of claim 1, wherein the characteristic data of the tissue is received from a palpation device.

8. The method of claim 1, wherein a location head provides positional data associating the characteristic data detected by the palpation device with the portion of the image relating to the first and the second coordinate of the tissue detected.

9. The method of claim 1, wherein the characteristic data is selected from the group consisting of tissue density, temperature, color, resistance, conductivity, impedance, ultrasound and sampling information.

10. The method of claim 1, wherein the characteristic data is selected from the group consisting of a distance traveled by a palpation probe, a velocity of travel of the palpation probe and a time of palpation at each contact point.

11. The method of claim 1, further comprising the step of receiving characteristic data of the tissue for each portion of the image for each of a plurality of third coordinate values and data describing the respective third coordinate value of the tissue relative to the subject body for each portion of the image.

12. The method of claim 11, wherein multiple image layers can be displayed, each image layer corresponding to a different incremental third coordinate value of the tissue relative to the subject body, each respective portion of the multiple image layers having similar first and second coordinates of the tissue relative to the subject body.

13. The method of claim 12, wherein the multiple image layers are displayed simultaneously, one over another, to create a virtual, three-dimensional image, whereby locating, in three-dimensions, tissue anomalies within the subject body is possible through inspection of the three-dimensional color image.

14. The method of claim 13, wherein the color displayed for each portion of the three-dimensional image is selected based on a formula that considers the characteristic data of the tissue for each layer simultaneously displayed for that respective portion.

15. The method of claim 14, wherein the formula is weighted, giving greater consideration to the characteristic data of the tissue for layers in closer proximity to the layer displayed by the threedimensional image.

16. The method of claim 11, further including the step of calculating and recording a three-dimensional size for tissue of pre-determined characteristic value.

17. A method for imaging tissue characteristics, comprising the steps of:

a. developing an image of tissue, the image divided into pre-determined portions and accompanied by data describing a first and a second coordinate of the tissue relative to a subject body for each portion of the image;

b. receiving characteristic data of the tissue for each portion of the image, each portion of the image having a first and a second coordinate relative to the image;

c. associating a code to the characteristic data for each portion of the image;

d. associating a color to each code; and

e. displaying the color for each portion of the image, whereby differing colors displayed over the image assist in determining the existence of tissue anomalies.

18. The method of claim 17, wherein each portion of the image is a pixel.

19. The method of claim 17, further including the step of calculating and recording a size for tissue of pre-determined characteristic value.

20. The method of claim 17, wherein the characteristic data includes data determined for each of a plurality of properties.

21. The method of claim 20, wherein a different set of codes is assigned to each of the plurality of properties.

22. The method of claim 21, wherein associating a color to each code associates a color to a resultant code, the resultant code calculated based on a formula that considers each of the plurality of properties and a respective value of the data determined for each property.

23. The method of claim 22, wherein the formula provides a pre-determined weight for each property and for the respective value of the data determined for each property.

24. The method of claim 17, wherein the characteristic data is density.

25. The method of claim 17, wherein the characteristic data is selected from the group consisting of tissue density, temperature, color, resistance, conductivity, impedance, ultrasound and sampling information.

26. The method of claim 17, wherein the characteristic data is selected from the group consisting of a distance traveled by a palpation probe, a velocity of travel of the palpation probe and a time ofpalpation at each contact point.

27. The method of claim 17, further comprising the step of receiving characteristic data of the tissue for each portion of the image for each of a plurality of third coordinate values and data describing the respective third coordinate value of the tissue relative to the subject body for each portion of the image.

28. The method of claim 27, wherein multiple image layers can be displayed, each image layer corresponding to a different incremental third coordinate value of the tissue relative to the subject body, each respective portion of the multiple image layers having similar first and second coordinates of the tissue relative to the subject body.

29. The method of claim 28, wherein the multiple image layers are displayed simultaneously, one over another, to create a virtual, three-dimensional image, whereby locating, in three-dimensions, tissue anomalies within the subject body is possible through inspection of the three-dimensional color image.

30. The method of claim 29, wherein the color displayed for each portion of the three-dimensional image is selected based on a formula that considers the characteristic data of the tissue for each layer simultaneously displayed for that respective portion.

31. The method of claim 30, wherein the formula is weighted, giving greater consideration to the characteristic data of the tissue for layers in closer proximity to the layer displayed by the three-dimensional image.

32. The method of claim 27, further including the step of calculating and recording a three-dimensional size for tissue of pre-determined characteristic value.

33. A method for creating color images of tissue density, comprising the steps of:

a. developing an image of tissue, the image divided into predetermined portions and accompanied by data describing a first and a second coordinate of the tissue relative to a subject body for each portion of the image;

b. receiving a density value of the tissue for each portion of the image, each portion of the image having a first and a second coordinate relative to the image;

c. associating a color to the density value for each portion of the image; and

d. displaying the color for each portion of the image, whereby different colors displayed over the image relate to different densities of tissue and thereby assist in determining the existence of tissue anomalies.

34. A method for creating three-dimensional color images of tissue density, comprising the steps of:

a. developing an image of tissue, the image divided into pre-determined portions and accompanied by data describing a first and a second coordinate of the tissue relative to a subject body for each portion of the image;

b. receiving a density value of the tissue for each portion of the image, each portion of the image having a first and a second coordinate relative to the image;

c. receiving a density value of the tissue for each portion of the image for each of a plurality of third coordinate values and data describing the respective third coordinate value of the tissue relative to the subject body for each portion of the image;

d. assigning a color for each portion of the image, the color assignment based on a formula that considers the density value of the tissue for each respective third coordinate value; and

e. displaying the color for each portion of the image, whereby different colors displayed over the image relate to different densities of tissue in three-dimensions, thereby assisting in determining the existence of tissue anomalies within the subject body.

35. The method of claim 34, wherein the formula is weighted, giving greater consideration to the density value of the tissue for third coordinate values in closer proximity to the third coordinate value displayed by the three-dimensional image.

36. The method of claim 34, further including the step of calculating and recording a three-dimensional size for tissue of pre-determined characteristic value.

37. A method for creating color images displaying tissue characteristics, comprising the steps of:

a developing an image of tissue, the image divided into pre-determined portions and accompanied by data describing a first and a second coordinate of the tissue relative to a subject body for each portion of the image;

b. receiving characteristic data of the tissue for each portion of the image, wherein the characteristic data includes detected values for a plurality of properties;

c. determining a resultant code for the characteristic data, wherein a set of codes is associated with each property, a certain code within the set is associated with the detected value of the respective property, and the resultant code is calculated using a formula that considers each detected value and each property;

d. associating a color to each resultant code; and

e. displaying the color for each portion of the image, whereby differing colors displayed over the image assist in determining the existence and location of tissue anomalies.

38. A method for creating three-dimensional color images displaying tissue characteristics, comprising the steps of:

a. developing an image of tissue, the image divided into pre-determined portions and accompanied by data describing a first and a second coordinate of the tissue relative to a subject body for each portion of the image;

b. receiving characteristic data of the tissue for each portion of the image and for each portion of the image for each of a plurality of levels, wherein the characteristic data includes detected values for a plurality of properties;

c. determining a resultant code for the characteristic data for each portion of the image and for each portion of the image for each of a plurality of levels, wherein a set of codes is associated with each property, a certain code within the set is associated with the detected value of the respective property, and the resultant code is calculated using a formula that considers each detected value and each property;

d. assigning a color for each portion of the image, the color assignment based on a weighted formula that considers the resultant code for each of the plurality of levels for the respective portion of the image, the weighted formula giving greater consideration to the resultant code for respective levels in closer proximity to the level in the image; and

e. displaying the color for each portion of the image, whereby differing colors displayed over the image assist in determining the existence and location of tissue anomalies in three dimensions.

39. A method of displaying changes in tissue characteristics, over time, by color image, comprising the steps of:

a. developing an image of tissue, the image divided into pre-determined portions and accompanied by data describing coordinates of the tissue relative to a subject body for each portion of the image;

b. receiving characteristic data of the tissue for each portion of the image for separate instances in time, each portion of the image having a first and a second coordinate relative to the image;

c. determining a value of a difference in the characteristic data of the tissue for each portion of the image for the separate instances in time;

d. associating a color to the value of the difference in the characteristic data for each portion of the image; and

e. displaying the color for each portion of the image, whereby differing colors displayed over the image assist in determining the existence and location of changes in tissue characteristics over time for the subject body.

40. The method of claim 39, wherein determining the value of the difference in the characteristic data of the tissue for each portion of the image for the separate instances in time is based upon a formula that calculates the difference in the characteristic data for the separate instances in time, and degree thereof, for each portion of the image.

41. The method of claim 40, wherein associating a color to the value of the difference is based upon having a pre-determined color assigned to certain incremental values of difference in the characteristic data, whereby the color image provides a quick and accurate means to determine the existence, location and degree of difference, over time, in characteristic data of tissue for the subject body.

42. The method of claim 40, wherein the formula considers both a difference, in absolute value, of the characteristic data and a first derivative analysis of the characteristic data.

43. The method of claim 42, wherein the formula is weighted depending on the portion of the image, the formula giving greater weight to the first derivative analysis for portions of the image displaying a perimeter of a suspect mass and giving greater weight to the difference in absolute value of the characteristic data for interior portions of the suspect mass and for tissue of normal characteristic value.

44. The method of claim 39, wherein determining the value of the difference in the characteristic data relates to either determining a difference, in absolute value, of the characteristic data or to a first derivative analysis of the characteristic data.

45. A computer-readable medium that configures a computer system to perform a method for imaging tissue characteristics, the method comprising the steps of:

a. developing an image of tissue, the image divided into pre-determined portions and accompanied by data describing a first and a second coordinate of the tissue relative to a subject body for each portion of the image;

b. receiving characteristic data of the tissue for each portion of the image, each portion of the image having a first and a second coordinate relative to the image;

c. associating a color to the characteristic data for each portion of the image; and

d. displaying the color for each portion of the image, whereby differing colors displayed over the image assist in determining the existence of tissue anomalies in the subject body.

46. A computer-readable medium that configures a computer system to perform a method for imaging tissue characteristics, the method comprising the steps of:

a. developing an image of tissue, the image divided into pre-determined portions and accompanied by data describing a first and a second coordinate of the tissue relative to a subject body for each portion of the image;

b. receiving characteristic data of the tissue for each portion of the image, each portion of the image having a first and a second coordinate relative to the image;

c. associating a code to the characteristic data for each portion of the image;

d. associating a color to each code; and

e. displaying the color for each portion of the image, whereby differing colors displayed over the image assist in determining the existence of tissue anomalies.

47. A computer-readable medium that configures a computer system to perform a method for creating color images of tissue density, the method comprising the steps of:

a. developing an image of tissue, the image divided into pre-determined portions and accompanied by data describing a first and a second coordinate of the tissue relative to a subject body for each portion of the image;

b. receiving a density value of the tissue for each portion of the image, each portion of the image having a first and a second coordinate relative to the image;

c. associating a color to the density value for each portion of the image; and

d. displaying the color for each portion of the image, whereby different colors displayed over the image relate to different densities of tissue and thereby assist in determining the existence of tissue anomalies.

48. A computer-readable medium that configures a computer system to perform a method for creating three-dimensional color images of tissue density, the method comprising the steps of:

a. developing an image of tissue, the image divided into pre-determined portions and accompanied by data describing a first and a second coordinate of the tissue relative to a subject body for each portion of the image;

b. receiving a density value of the tissue for each portion of the image, each portion of the image having a first and a second coordinate relative to the image;

c. receiving a density value of the tissue for each portion of the image for each of a plurality of third coordinate values and data describing the respective third coordinate value of the tissue relative to the subject body for each portion of the image;

d. assigning a color for each portion of the image, the color assignment based on a formula that considers the density value of the tissue for each respective third coordinate value; and

e. displaying the color for each portion of the image, whereby different colors displayed over the image relate to different densities of tissue in three-dimensions, thereby assisting in determining the existence of tissue anomalies within the subject body.

49. A computer-readable medium that configures a computer system to perform a method for creating color images displaying tissue characteristics, the method comprising the steps of:

a. developing an image of tissue, the image divided into pre-determined portions and accompanied by data describing a first and a second coordinate of the tissue relative to a subject body for each portion of the image;

b. receiving characteristic data of the tissue for each portion of the image, wherein the characteristic data includes detected values for a plurality of properties;

c. determining a resultant code for the characteristic data, wherein a set of codes is associated with each property, a certain code within the set is associated with the detected value of the respective property, and the resultant code is calculated using a formula that considers each detected value and each property;

d. associating a color to each resultant code; and

e. displaying the color for each portion of the image, whereby differing colors displayed over the image assist in determining the existence and location of tissue anomalies.

50. A computer-readable medium that configures a computer system to perform a method for creating three-dimensional color images displaying tissue characteristics, the method comprising the steps of:

a. developing an image of tissue, the image divided into pre-determined portions and accompanied by data describing a first and a second coordinate of the tissue relative to a subject body for each portion of the image;

b. receiving characteristic data of the tissue for each portion of the image and for each portion of the image for each of a plurality of levels, wherein the characteristic data includes detected values for a plurality of properties;

c. determining a resultant code for the characteristic data for each portion of the image and for each portion of the image for each of a plurality of levels, wherein a set of codes is associated with each property, a certain code within the set is associated with the detected value of the respective property, and the resultant code is calculated using a formula that considers each detected value and each property;

d. assigning a color for each portion of the image, the color assignment based on a weighted formula that considers the resultant code for each of the plurality of levels for the respective portion of the image, the weighted formula giving greater consideration to the resultant code for respective levels in closer proximity to the level in the image; and

e. displaying the color for each portion of the image, whereby differing colors displayed over the image assist in determining the existence and location of tissue anomalies in three dimensions.

51. A computer-readable medium that configures a computer system to perform a method of displaying changes in tissue characteristics, over time, by color image, the method comprising the steps of:

a. developing an image of tissue, the image divided into pre-determined portions and accompanied by data describing coordinates of the tissue relative to a subject body for each portion of the image;

b. receiving characteristic data of the tissue for each portion of the image for separate instances in time, each portion of the image having a first and a second coordinate relative to the image;

c. determining a value of a difference in the characteristic data of the tissue for each portion of the image for the separate instances in time;

d. associating a color to the value of the difference in the characteristic data for each portion of the image; and

e. displaying the color for each portion of the image, whereby differing colors displayed over the image assist in determining the existence and location of changes in tissue characteristics over time for the subject body.

52. A computer-readable medium that stores a program for imaging tissue characteristics, the program comprising:

a. means for developing an image of tissue, the image divided into pre-determined portions and accompanied by data describing a first and a second coordinate of the tissue relative to a subject body for each portion of the image;

b. means for receiving characteristic data of the tissue for each portion of the image, each portion of the image having a first and a second coordinate relative to the image;

c. means for associating a color to the characteristic data for each portion of the image; and

d. means for displaying the color for each portion of the image, whereby differing colors displayed over the image assist in determining the existence of tissue anomalies in the subject body.

53. A computer-readable medium that stores a program for imaging tissue characteristics, the program comprising:

a. means for developing an image of tissue, the image divided into pre-determined portions and accompanied by data describing a first and a second coordinate of the tissue relative to a subject body for each portion of the image;

b. means for receiving characteristic data of the tissue for each portion of the image, each portion of the image having a first and a second coordinate relative to the image;

c. means for associating a code to the characteristic data for each portion of the image;

d. means for associating a color to each code; and

e. means for displaying the color for each portion of the image, whereby differing colors displayed over the image assist in determining the existence of tissue anomalies.

54. A computer-readable medium that stores a program for creating color images of tissue density, the program comprising:

a. means for developing an image of tissue, the image divided into pre-determined portions and accompanied by data describing a first and a second coordinate of the tissue relative to a subject body for each portion of the image;

b. means for receiving a density value of the tissue for each portion of the image, each portion of the image having a first and a second coordinate relative to the image;

c. means for associating a color to the density value for each portion of the image; and

d. means for displaying the color for each portion of the image, whereby different colors displayed over the image relate to different densities of tissue and thereby assist in determining the existence of tissue anomalies.

55. A computer-readable medium that stores a program for creating three-dimensional color images of tissue density, the program comprising:

a. means for developing an image of tissue, the image divided into pre-determined portions and accompanied by data describing a first and a second coordinate of the tissue relative to a subject body for each portion of the image;

b. means for receiving a density value of the tissue for each portion of the image, each portion of the image having a first and a second coordinate relative to the image;

c. means for receiving a density value of the tissue for each portion of the image for each of a plurality of third coordinate values and data describing the respective third coordinate value of the tissue relative to the subject body for each portion of the image;

d. means for assigning a color for each portion of the image, the color assignment based on a formula that considers the density value of the tissue for each respective third coordinate value; and

e. means for displaying the color for each portion of the image, whereby different colors displayed over the image relate to different densities of tissue in three-dimensions, thereby assisting in determining the existence of tissue anomalies within the subject body.

56. A computer-readable medium that stores a program for creating color images displaying tissue characteristics, the program comprising:

a. means for developing an image of tissue, the image divided into pre-determined portions and accompanied by data describing a first and a second coordinate of the tissue relative to a subject body for each portion of the image;

b. means for receiving characteristic data of the tissue for each portion of the image, wherein the characteristic data includes detected values for a plurality of properties;

c. means for determining a resultant code for the characteristic data, wherein a set of codes is associated with each property, a certain code within the set is associated with the detected value of the respective property, and the resultant code is calculated using a formula that considers each detected value and each property;

d. means for associating a color to each resultant code; and

e. means for displaying the color for each portion of the image, whereby differing colors displayed over the image assist in determining the existence and location of tissue anomalies.

57. A computer-readable medium that stores a program for creating three-dimensional color images displaying tissue characteristics, the program comprising:

a. means for developing an image of tissue, the image divided into pre-determined portions and accompanied by data describing a first and a second coordinate of the tissue relative to a subject body for each portion of the image;

b. means for receiving characteristic data of the tissue for each portion of the image and for each portion of the image for each of a plurality of levels, wherein the characteristic data includes detected values for a plurality of properties;

c. means for determining a resultant code for the characteristic data for each portion of the image and for each portion of the image for each of a plurality of levels, wherein a set of codes is associated with each property, a certain code within the set is associated with the detected value of the respective property, and the resultant code is calculated using a formula that considers each detected value and each property;

d. means for assigning a color for each portion of the image, the color assignment based on a weighted formula that considers the resultant code for each of the plurality of levels for the respective portion of the image, the weighted formula giving greater consideration to the resultant code for respective levels in closer proximity to the level in the image; and

e. means for displaying the color for each portion of the image, whereby differing colors displayed over the image assist in determining the existence and location of tissue anomalies in three dimensions.

58. A computer-readable medium that stores a program for displaying changes in tissue characteristics, over time, by color image, the program comprising:

a. means for developing an image of tissue, the image divided into pre-determined portions and accompanied by data describing coordinates of the tissue relative to a subject body for each portion of the image;

b. means for receiving characteristic data of the tissue for each portion of the image for separate instances in time, each portion of the image having a first and a second coordinate relative to the image;

c. means for determining a value of a difference in the characteristic data of the tissue for each portion of the image for the separate instances in time;

d. means for associating a color to the value of the difference in the characteristic data for each portion of the image; and

e. means for displaying the color for each portion of the image, whereby differing colors displayed over the image assist in determining the existence and location of changes in tissue characteristics over time for the subject body.