Compositions, targets, methods and devices for the therapy of ocular and periocular disorders
First Claim
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1. A method for treating a disorder in a mammal, said method comprising administering to said mammal an effective amount of a compound that reduces external pressure effects, thereby alleviating external pressure effects experienced by the mammal.
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Abstract
Methods for treating ocular and periocular disorders by administration to a human patient of a therapeutically effective amount of a compound that modulates muscle action.
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Citations
29 Claims
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1. A method for treating a disorder in a mammal, said method comprising
administering to said mammal an effective amount of a compound that reduces external pressure effects, thereby alleviating external pressure effects experienced by the mammal.
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11. A method for maximizing the health of the optic nerve and retina in eye disorders by increasing retinal and optic nerve blood flow, said method comprising the steps of
applying to the eye an effective amount of a compound that reduces external pressure effects on the eye in an amount effective to effect such reduction thereby alleviating the pressure inside the eye and increasing blood flow to the eye.
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14. A method for reducing a volume of extraocular muscles, said method comprising the steps of
administering in an enlarged muscle a myotoxic compound in sufficient amounts to reduce the volume of said enlarged muscle.
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16. A method for improving an outcome of refractive surgery, said method comprising the steps of
applying to the eye an effective amount of a compound that reduces external pressure effects on the eye in an amount effective to effect such reduction.
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17. A method for improving an outcome of eye surgery for patients with glaucoma, said method comprising the steps of
applying to the eye an effective amount of a compound that reduces external pressure effects on the eye in an amount effective to effect such reduction thereby alleviating an increase of or spike in eye pressure after surgery.
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19. A method for determining an amount of a compound to be administered to a mammal in order to achieve an efficacy needed, the method comprising
a first step of evaluating external pressure effects using lid measuring devices, and a second step of applying a certain amount of said compound to the mammal based on the results acquired in the first step.
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22. A method for treating at least one of glaucoma, ocular hypertension and optic neuropathy in a mammal, said method comprising
administering to said mammal botulinum toxin, thereby alleviating pressure effects.
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24. A method of protecting against neural damage in a mammal, said method comprising
administering to said mammal an effective amount of a compound that is a neural protective agent, wherein said compound is at least one of botulinum toxin, gabapentin, lidocaine, mexiletine, selegiline and ketamine.
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26. A method of treating a patient for a cosmetic purpose, said method comprising the steps of
administering an effective amount of a combination of lidocaine and alcohol to the patient.
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28. A method of increasing therapeutic efficacy of eye drops to treat glaucoma of a patient, said method comprising
administering to said patient an effective amount of a compound that reduces external pressure effects.
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