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Quality assurance/quality control for high throughput bioassay process

  • US 20040058388A1
  • Filed: 07/28/2003
  • Published: 03/25/2004
  • Est. Priority Date: 07/29/2002
  • Status: Active Grant
First Claim
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1. A method, comprising:

  • selecting a diverse group of sera, the diverse group of sera having different characteristics;

    applying each of the diverse group of sera to at least one spot on a plurality of different biochips;

    performing mass spectrometry on each of said plurality of biochips;

    generating a biochip model based at least in part on the spectra obtained from the plurality of different sera and biochips;

    applying a test serum to a spot on a biochip;

    performing mass spectrometry on the test serum to obtain a spectrum associated with the test serum;

    mapping the spectrum obtained from said performing to the biochip model; and

    determining whether the spectrum maps to the biochip model.

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