Multi-layer and multi-section coils for guide wire

• US 20040059258A1
• Filed: 07/07/2003
• Published: 03/25/2004
• Est. Priority Date: 10/05/2000
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Original Assignee: Scimed Life Systems Incorporated (Boston Scientific Corporation)
• Inventors: Zhou, Pu, Eungard, Todd D., Campion, Jon T.
• Granted Patent: US 7,097,624 B2
• Time in Patent Office: Days
• US Class Current: 600/585
• CPC Class Codes: A61M 2025/09083 having a coil around a core
• CPC Class Codes: A61M 25/09 Guide wires

Abstract

A guide wire having a coil disposed over the guide wire, wherein the coil is integrally formed of a single wire and has regions of differing properties over its length. Some wire embodiments have longitudinally alternating layer segments having differing properties including radiopacity, lubricity, hydrophilicity, hemo-compatibility, flexibility, malleability, stiffness, and shape memory properties. A coil formed according to the present invention may have numerous distinct property segments, while being formed from only a single wire and requiring only two points for affixation to the guide wire. One wire according to the present invention is made by coating a core wire with alternating materials having different properties. Another wire has alternating layer segments including radiopaque material, such as radiopaque loaded polymer, or a radiopaque metal, bonded to the core wire. One embodiment wire includes alternating regions having the lubricity and/or hydrophilicity varied as between the distal and proximal regions. Some embodiments have alternating regions of varying radiopacity, further having a polymeric coating or layer thereover. In yet other embodiments, a tie-layer is disposed between the core wire and the outer polymeric layer, to serve as a polymer substrate to assist in binding the outer layer to the central core wire. Some embodiments use alternating application of ionizing radiation, a binding agent, or a release agent, to vary the adhesion strength of subsequently applied material over alternating regions, so as to enable removing the subsequently applied material selectively in a subsequent removal step.

Claims

1. A method for making a guide wire having a coil, comprising the steps of:

providing a core wire;

providing a wire;

generating a first property over a first section of said wire;

generating a second property over a second section of said wire, said second property being different from said first property;

forming said wire into a coil; and

securing said coil to said guide wire.

2. A method for making a guide wire as in claim 1, wherein said first and second properties are selected from the group consisting of radiopacity, lubricity, hydrophilicity, hemocompatibility, flexibility, malleability, stiffness, and shape memory.

3. A method for making a guide wire as in claim 1, wherein said first property generating step includes creating a first material layer over said first section, said first material layer providing at least part of said first property.

4. A method for making a guide wire as in claim 3, wherein said creating first material layer step includes creating a first material layer having a greater radiopacity than said second material radiopacity.

5. A method for making a guide wire as in claim 3, wherein said creating first material layer step includes plating a highly radiopaque first material over said wire first section, but not plating a highly radiopaque material over said wire second section, such that said first wire section is more radiopaque than said second wire section.

6. A method for making a guide wire as in claim 3, wherein said first material layer creating step includes creating a first material coating over said first section.

7. A method for making a guide wire as in claim 1, wherein said second property generating step includes creating a second material layer over said second section, said second material layer providing at least part of said second property.

8. A method for making a guide wire as in claim 7, wherein said second material layer creating step includes creating a second material coating over said second section.

9. A method for making a guide wire as in claim 6, wherein said first material coating creating step includes treating said first wire section to enhance binding of said first material to said wire, further comprising creating a first material layer over said second wire section, and removing said first material layer from said second wire section.

10. A method for making a guide wire as in claim 9, wherein said second wire section is not treated to enhance binding of said first material to said second wire section.

11. A method for making a guide wire as in claim 9, wherein said first wire section treating step includes exposing said first guide wire section to ionizing radiation.

12. A method for making a guide wire as in claim 9, wherein said first wire section treating step includes forming a tie-layer over said first wire section.

13. A method for making a guide wire as in claim 6, wherein said first material coating creating step includes treating said second wire portion to inhibit binding of said first material to said wire, further comprising creating a first material layer over said second wire section, and removing said first material from said second wire section.

14. A method for making a guide wire as in claim 13, wherein said first wire section is not treated to inhibit binding of said first material to said first wire section.

15. A method for making a guide wire distal portion as in claim 13, wherein said second wire section inhibiting binding step includes applying a release agent to said second wire section.

16. A method for making a guide wire as in claim 1, wherein said method includes making a plurality of said first sections and said second sections.

17. A method for making a guide wire as in claim 16, wherein said coil has a length, wherein said method includes making a plurality of alternating said first wire sections and said second wire sections, such that said coil has a plurality of said first and second properties disposed over said length.

18. A method for making a guide wire as in claim 17, wherein said first and second properties differ in radiopacity.

19. A method for making a guide wire as in claim 18, wherein a majority of said first wire sections are disposed at regular intervals therebetween over said length.

20. A guide wire including a distal portion having a coil disposed about said guide wire distal portion, said coil being integrally formed, having a first property over a first section of said coil, having a second property over a second section of said wire, wherein said second property is different from said first property.

21. A guide wire as in claim 20, wherein said first and second properties are selected from the group consisting of radiopacity, lubricity, hydrophilicity, hemocompatibliity, flexibility, malleability, stiffness, and shape memory.

22. A guide wire as in claim 20, wherein at least some of said first property is provided by a first material sleeve disposed over said first coil section but not over said second coil section.

23. A guide wire as in claim 20, wherein at least some of said first property is provided by a first material coating disposed over said first coil section but not over said second coil section.

24. A guide wire as in claim 23, wherein said coil has a plurality of said first and second sections.

25. A guide wire as in claim 24, wherein said coil has a plurality of alternating said first sections and said second sections.

26. A guide wire as in claim 25, wherein said first and second properties differ in radiopacity from each other.

27. A guide wire as in claim 26, wherein a majority of said first wire sections are disposed at regular intervals therebetween over said lengths.

28. A guide wire as in claim 20, wherein said first and seconds properties differ in radiopacity from each other.