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Sterile filling machine having needle filling station within e-beam chamber

  • US 20040060261A1
  • Filed: 06/19/2003
  • Published: 04/01/2004
  • Est. Priority Date: 06/19/2002
  • Status: Active Grant
First Claim
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1. A method for sterile filling a container with a substance, wherein the container includes a heat resealable stopper and a chamber for receiving the substance therein, the method comprising the steps of:

  • sealing the stopper to the container;

    transporting the sealed, empty containers through an e-beam chamber;

    directing an electron beam within the e-beam chamber onto a penetrable surface of the stopper to sterilize the penetrable surface;

    introducing a needle within the e-beam chamber through the sterilized penetrable surface of the stopper;

    introducing through the needle a substance into the chamber of the container;

    withdrawing the needle from the stopper upon introducing the substance through the needle and into the chamber;

    transporting the filled containers out of the e-beam chamber; and

    applying energy to the penetrated surface of the stopper and hermetically sealing same.

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