Medical devices having durable and lubricious polymeric coating

• US 20040071988A1
• Filed: 10/03/2003
• Published: 04/15/2004
• Est. Priority Date: 10/11/2002
• Status: Active Grant

• Current Assignee: Ethicon Incorporated (Johnson & Johnson)
• Original Assignee: Ethicon Incorporated (Johnson & Johnson)
• Inventors: Nawrocki, Jesse G., Jamiolkowski, Dennis D.
• Granted Patent: US 7,041,088 B2
• Time in Patent Office: Days
• US Class Current: 428/450
• CPC Class Codes: A61B 17/06066 Needles, e.g. needle tip configurations making needles B21G1/00
• CPC Class Codes: A61B 17/3211 Surgical scalpels, knives; Accessories therefor
• CPC Class Codes: A61L 2420/06 Coatings containing a mixture of two or more compounds
• CPC Class Codes: A61L 29/085 Macromolecular materials
• CPC Class Codes: A61L 29/14 Materials characterised by their function or physical properties , e.g. lubricating compositions
• CPC Class Codes: A61L 31/10 Macromolecular materials
• CPC Class Codes: A61L 31/14 Materials characterised by their function or physical properties , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
• CPC Class Codes: C08G 77/16 to hydroxyl groups
• CPC Class Codes: C08L 23/06 Polyethene
• CPC Class Codes: C08L 23/12 Polypropene
• CPC Class Codes: C08L 67/04 Polyesters derived from hydroxycarboxylic acids, e.g. lactones C08L67/06 takes precedence
• CPC Class Codes: C08L 83/04 Polysiloxanes
• CPC Class Codes: Y10T 428/31663 As siloxane, silicone or silane
• CPC Class Codes: Y10T 428/31855 Of addition polymer from unsaturated monomers

Abstract

A medical device having a contact surface exposed repeatedly to bodily tissue is disclosed. The contact surface is coated with a silicone polymer and one or more non-silicone hydrophobic polymers. The preferred medical device is a surgical needle, and the preferred coating is a polydimethylsiloxane and polypropylene wax hydrocarbon mixture. The incorporation of the non-silicone hydrophobic polymer increases the durability of the coating on the device without sacrificing lubricity.

Claims

1. A medical device having a contact surface exposed repeatedly to bodily tissue, the contact surface being coated with an effective amount of a coating comprising a silicone polymer and a non-silicone hydrophobic polymer.

2. The medical device of claim 1 wherein the coating comprises a mixture of the silicone polymer and the non-silicone hydrophobic polymer.

3. The medical device of claim 1 wherein the coating comprises an inner layer of the non-silicone hydrophobic polymer and an outer layer of the silicone polymer.

4. The medical device of claim 1 wherein the silicone polymer is a polysiloxane.

5. The medical device of claim 4 wherein the polysiloxane is a polyalkylsiloxane.

6. The medical device of claim 5 wherein the polyalkylsiloxane is a polydimethylsiloxane.

7. The medical device of claim 6 wherein the non-silicone hydrophobic polymer has a critical surface tension of less than about 50 mN/m.

8. The medical device of claim 7 wherein the non-silicone hydrophobic polymer is a thermoplastic polymer.

9. The medical device of claim 8 wherein the thermoplastic polymer is flowable at less than about 210°

C.

10. The medical device of claim 9 wherein the coating has about 40 to about 86 weight percent of the polydimethylsiloxane and about 14 to about 60 weight percent of the thermoplastic polymer.

11. The medical device of claim 10 wherein the coating has about 44 to about 66 weight percent of the polydimethylsiloxane and about 34 to about 56 weight percent of the thermoplastic polymer.

12. The medical device of claim 11 wherein the medical device is a surgical needle.

13. The medical device of claim 12 wherein the polydimethylsiloxane is hydroxy terminated.

14. The medical device of claim 13 wherein the thermoplastic polymer is polyethylene, polypropylene or polycaprolactone.

15. The medical device of claim 2 wherein the coating comprises a mixture of an hydroxy terminated polydimethylsiloxane and a non-silicone hydrophobic polymer selected from the group consisting of polyethylene, polypropylene and polycaprolactone.

16. The medical device of claim 15 wherein the coating mixture has about 44 to about 66 weight percent of the hydroxy terminated polydimethylsiloxane and about 34 to about 56 weight percent of the non-silicone hydrophobic polymer.

17. The medical device of claim 16 wherein the medical device is a surgical needle.