Device for measuring blood coagulation and method thereof
First Claim
1. A device for the measurement of clotting times of a fluid comprising an inlet port for the collection of the fluid sample and in fluid connection with at least a microchannel, whereby at least two electrodes are situated along the length of the microchannel.
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Accused Products
Abstract
A device and method for measuring the clotting times in a fluid, typically blood, within a microchannel whereby the onset of clotting is determined by measurement of the rate of change or value of capacitance or impedance between two electrodes situated on either side of the microchannel. There is provided a disposable test-strip (100) comprising an upper and lower support (101) and (103). A microchannel (102) is formed into the upper surface of the lower support member (103). A second substrate layer (101) is laminated on top of the support member (103), thereby closing the open microchannel (102). Electrodes (104) are formed on the respective outer surfaces of the substrate layers and coplanar to the channel.
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Citations
15 Claims
- 1. A device for the measurement of clotting times of a fluid comprising an inlet port for the collection of the fluid sample and in fluid connection with at least a microchannel, whereby at least two electrodes are situated along the length of the microchannel.
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13. A method of measuring the clotting times of a fluid comprising introducing the fluid sample into a microchannel, whereby the total distance of flow of the fluid within a microchannel is determined by a measurement of the ratio of capacitance or impedance of the filled to the unfilled portion of the channel.
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14. A method of measuring the clotting times of a fluid comprising introducing the fluid sample into a microchannel whereby the speed of flow of fluid within the microchannel is determined by measuring the rate of change of capacitance or impedance.
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15. A method of measuring the clotting times of a fluid comprising introducing the fluid sample into a microchannel whereby the coagulative state of the fluid within the microchannel is determined by measuring the rate of change of capacitance or impedance of the fluid.
Specification