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Low dead volume extraction column device

  • US 20040072375A1
  • Filed: 07/14/2003
  • Published: 04/15/2004
  • Est. Priority Date: 07/15/2002
  • Status: Active Grant
First Claim
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1. A low dead volume extraction column comprising:

  • i) a column body having an open upper end for attachment to a pump, an open lower end for passing fluid into and out of the column body, and an open channel between the upper and lower end of the column body;

    ii) a bottom frit bonded to and extending across the open channel, the bottom frit having a low pore volume;

    iii) a top frit bonded to and extending across the open channel between the bottom frit and the open upper end of the column body, the top frit having a low pore volume, wherein the top frit, bottom frit, and channel surface define an extraction media chamber; and

    iv) a bed of extraction media positioned inside the extraction media chamber.

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