Antidepressant dosage form
First Claim
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1. A therapeutic composition comprising 0.5 mg to 750 mg of a drug of the formula:
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Abstract
The invention pertains to a dosage form 10 and to administering an antidepressant medicament 16 for an extended period of time in a rate-known dose.
34 Citations
7 Claims
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1. A therapeutic composition comprising 0.5 mg to 750 mg of a drug of the formula:
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2. A therapeutic composition comprising 0.5 mg to 750 mg of a drug of the formula;
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3. A therapeutic composition comprising 0.5 mg to 750 mg of a drug of the formula:
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4. A method for administering a drug to the gastrointestinal tract of an animal, wherein the method comprises:
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(a) admitting orally into the animal a dosage form comprising a drug of the formula;
which drug possesses antidepressant therapy and the dosage form comprises a member selected from the group consisting of a sustained-release dosage form and a controlled-release dosage form; and
,(b) administering the drug from the dosage form over an extended period of time in a therapeutically responsive dose to produce the antidepressant therapy.
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5. A dosage form for administering a drug to an environment of use, wherein the dosage form comprises a drug of the formula:
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6. A dosage form for the oral delivery of a drug to an environment of use, wherein the dosage form comprises:
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(a) a wall comprising at least in part a composition permeable to the passage of fluid, which wall surrounds;
(b) a compartment;
(c) a drug composition in the compartment comprising a drug of the formula;
wherein the dotted line represents a member selected from the group consisting of an unsaturation and cycloalkenyl group;
R1 is a member selected from the group consisting of hydrogen and alkyl of 1 to 6 carbon atoms;
R2 is a member selected from the group consisting of hydrogen and alkyl of 1 to 6 carbon atoms;
R4 is a member selected from the group consisting of hydrogen, alkyl of 1 to 6 carbon atoms, formyl, and alkanoyl of 2 to 7 carbon atoms;
R5 and R6 are independently a member selected from the group consisting of hydrogen, hydroxyl and alkyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, alknaoyloxy of 2 to 7 carbon atoms, nitro, alkylmercapto of 1 to 6 carbon atoms, amino, alkylamino of 1 to 6 carbon atoms, alkanamido of 2 to 7 carbon atoms, halo and trifluoroethyl;
R7 is a member selected from the group consisting of hydrogen and alkyl of 1 to 6 carbons;
an n is 0 to 4; and
(d) a displacement in the compartment comprising a composition comprising an osmotically active compound; and
,(e) an exit passageway in the dosage form for delivering the drug composition from the dosage form. - View Dependent Claims (7)
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Specification