Diagnosis support system for diabetes

• US 20040091424A1
• Filed: 11/05/2003
• Published: 05/13/2004
• Est. Priority Date: 11/06/2002
• Status: Abandoned Application

• Current Assignee: Sysmex Corporation
• Original Assignee: Sysmex Corporation
• Inventors: Kouchi, Yasuhiro, Nakajima, Hiromu, Saitou, Takeo, Kishi, Kazuki, Asano, Kaoru
• Application Number:
  US10/700,672
• Publication Number:
  US 20040091424A1
• Time in Patent Office: Days
• US Class Current: 424/9.1
• CPC Class Codes: G16H 10/20 for electronic clinical trials or questionnaires
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 20/60 relating to nutrition control, e.g. diets
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems
• CPC Class Codes: G16H 50/50 for simulation or modelling of medical disorders
• CPC Class Codes: G16H 50/70 for mining of medical data, e.g. analysing previous cases of other patients

Abstract

A diagnosis support system for diabetes has: a diagnostic data input unit for entering diagnostic data including the clinical testing data and clinical findings of the patient; a pathophysiologic condition pattern analyzing unit for analyzing the pathophysiologic condition of diabetes of the patient by comparing the diagnostic data and a predetermined criteria of analysis; a diagnosis support information generating unit for generating diagnosis support information based on the diagnostic data and diagnostic criteria of determination determined by each analyzed pathophysiologic condition, and a diagnosis support information output unit for supplying information obtained by the pathophysiologic condition pattern analyzing unit and the diagnostic information generating unit.

Claims

1. A diagnosis support system for diabetes comprising:

a diagnostic data input unit for entering diagnostic data including clinical testing data and clinical findings of a patient;

a pathophysiologic condition pattern analyzing unit for analyzing the pathophysiologic condition of diabetes of the patient by comparing the diagnostic data and predetermined criteria of analysis;

a diagnosis support information generating unit for generating diagnosis support information based on the diagnostic data and criteria of diagnosis predetermined for each analyzed pathophysiologic condition, and

a diagnosis support information output unit for outputting information obtained by the pathophysiologic condition pattern analyzing unit and the diagnostic information generating unit.

2. A diagnosis support system for diabetes according to claim 1, wherein the pathophysiologic condition pattern analyzing unit comprises the criteria of analysis including determination of peripheral insulin resistance, determination of hepatic glucose production, determination of glucose toxicity as a result of being subjected to hyperglycemia for a long time, and determination of decrease of insulin secretion, and analyses the pathophysiologic condition of diabetes by calculating evaluation values obtained from each criterion of analysis, and comparing the obtained evaluation values.

3. A diagnosis support system for diabetes according to claim 2, wherein the diagnosis support information generating unit generates diagnosis support information for treatment of the patient using the criteria of diagnosis including a standard of treatment policy for the patient whose evaluation value of peripheral insulin resistance is the largest, a standard of treatment policy for the patient whose evaluation value of hepatic glucose production is the largest, a standard of treatment policy for the patient whose evaluation value of glucose toxicity as a result of being subjected to hyperglycemia for a long time is the largest, and a standard of treatment policy for the patient whose evaluation value of decrease of insulin secretion is the largest.

4. A diagnosis support system for diabetes according to claim 2 or 3, wherein the diagnosis support information generated by the diagnosis support information generating unit includes information on the analyzed pathophysiologic condition including the evaluation value and information on exercise therapy, dietetic therapy, and medicinal treatment.

5. A diagnosis support system for diabetes according to claim 1, further comprising:

a biomodel generating unit for generating a biomodel by estimating a patient-specific biological parameter of diabetes using the entered diagnostic data and information on the pathophysiologic condition analyzed by the pathophysiologic condition pattern analyzing unit, and

a pathophysiologic condition simulation unit for estimating the pathophysiologic condition after treatment by giving the generated biomodel a predetermined treatment based on a virtual treatment policy in a simulating manner.

6. A diagnosis support program for diabetes for allowing a computer to implement a diagnostic data input function for allowing input of diagnostic data including clinical testing data and clinical findings of a patient, a pathophysiologic condition pattern analyzing function for analyzing the pathophysiologic condition of diabetes of the patient by comparing the diagnostic data and predetermined criteria of analysis, a diagnosis support information generating function for generating diagnosis support information by using the diagnostic data and criteria of diagnosis predetermined for each analyzed pathophysiologic condition, and a diagnosis support information output function for outputting information obtained by the pathophysiologic condition pattern analyzing function and the diagnostic information generating function.

7. A diagnosis support program for diabetes according to claim 6, wherein the pathophysiologic condition pattern analyzing function comprises the criteria of analysis including determination of peripheral insulin resistance, determination of hepatic glucose production, determination of glucose toxicity as a result of being subjected to hyperglycemia for a long time, and determination of decrease of insulin secretion, and analyses the pathophysiologic condition of diabetes by calculating evaluation value obtained from each criterion of analysis, and analysis, and comparing the obtained evaluation values.

8. A diagnosis support program for diabetes according to claim 7, wherein the diagnosis support information generating function generates diagnosis support information for treatment of the patient using the criteria of diagnosis including a standard of treatment policy for the patient whose evaluation value of peripheral insulin resistance is the largest, a standard of treatment policy for the patient whose evaluation value of hepatic glucose production is the largest, a standard of treatment policy for the patient whose evaluation value of glucose toxicity as a result of being subjected to hyperglycemia for a long time is the largest, and a standard of treatment policy for the patient whose evaluation value of decrease of insulin secretion is the largest.

9. A diagnosis support program for diabetes according to claim 7 or 8, wherein the diagnosis support information generated by the diagnosis support information generating function includes information on the analyzed pathophysiologic condition including the evaluation value and information on exercise therapy, dietetic therapy, and medicinal treatment.

10. A diagnosis support program for diabetes according to claim 6, further comprising:

a biomodel generating function for generating a biomodel by estimating a patient-specific biological parameter of diabetes using the entered diagnostic data and information on the pathophysiologic condition analyzed by the pathophysiologic condition pattern analyzing function, and

a pathophysiologic condition simulation function for estimating the pathophysiologic condition after treatment by giving the generated biomodel a predetermined treatment based on a virtual treatment policy in a simulating manner.

11. A diagnosis method of a diagnosis support system for diabetes comprising:

a diagnostic data input step for entering diagnostic data including clinical testing data and clinical findings of a patient;

a pathophysiologic condition pattern analyzing step for analyzing the pathophysiologic condition of diabetes of the patient by comparing the diagnostic data and predetermined criteria of analysis;

a diagnosis support information generating step for generating diagnosis support information based on the diagnostic data and criteria of diagnosis predetermined for each analyzed pathophysiologic condition, and

a diagnosis support information output step for outputting information obtained by the pathophysiologic condition pattern analyzing step and the diagnostic information generating step.

12. A diagnosis method of a diagnosis support system for diabetes according to claim 11, wherein the pathophysiologic condition pattern analyzing step comprises the criteria of analysis including determination of peripheral insulin resistance, determination of hepatic glucose production, determination of glucose toxicity as a result of being subjected to hyperglycemia for a long time, and determination of decrease of insulin secretion, and analyses the pathophysiologic condition of diabetes by calculating evaluation values obtained from each criterion of analysis, and comparing the obtained evaluation values.

13. A diagnosis method of a diagnosis support system for diabetes according to claim 12, wherein the diagnosis support information generating step generates diagnosis support information for treatment of the patient using the criteria of diagnosis including a standard of treatment policy for the patient whose evaluation value of peripheral insulin resistance is the largest, a standard of treatment policy for the patient whose evaluation value of hepatic glucose production is the largest, a standard of treatment policy for the patient whose evaluation value of glucose toxicity as a result of being subjected to hyperglycemia for a long time is the largest, and a standard of treatment policy for the patient whose evaluation value of decrease of insulin secretion is the largest.

14. A diagnosis method of a diagnosis support system for diabetes according to claim 12 or 13, wherein the diagnosis support information generated by the diagnosis support information generating step includes information on the analyzed pathophysiologic condition including the evaluation value and information on exercise therapy, dietetic therapy, and medicinal treatment.

15. A diagnosis method of a diagnosis support system for diabetes according to claim 11, further comprising:

a biomodel generating step for generating a biomodel by estimating a patient-specific biological parameter of diabetes using the entered diagnostic data and information on the pathophysiologic condition analyzed by the pathophysiologic condition pattern analyzing step, and

a pathophysiologic condition simulation step for estimating the pathophysiologic condition after treatment by giving the generated biomodel a predetermined treatment based on a virtual treatment policy in a simulating manner.