Method and apparatus for body fluid sampling with improved sensing

• US 20040092995A1
• Filed: 05/02/2003
• Published: 05/13/2004
• Est. Priority Date: 04/19/2002
• Status: Active Grant

• Current Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Original Assignee: Pelikan Technologies, Inc.
• Inventors: Boecker, Dirk, Freeman, Dominique M.
• Granted Patent: US 7,297,151 B2
• Time in Patent Office: Days
• US Class Current: 606/181
• CPC Class Codes: A61B 17/8863 Apparatus for shaping or cutting osteosynthesis equipment by medical personnel
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150152 by an adequate mechanical impact on the puncturing location
• CPC Class Codes: A61B 5/150167 Adjustable piercing speed of skin piercing element, e.g. blade, needle, lancet or canula, for example with varying spring force or pneumatic drive
• CPC Class Codes: A61B 5/150175 Adjustment of penetration depth
• CPC Class Codes: A61B 5/150213 Venting means
• CPC Class Codes: A61B 5/150305 Packages specially adapted for piercing devices or blood sampling devices kits for diabetes A61M5/003; packaging in general B65D
• CPC Class Codes: A61B 5/150358 Strips for collecting blood, e.g. absorbent optical reagent test strips G01N21/8483; chemical reagent test strips G01N33/4875, G01N33/52
• CPC Class Codes: A61B 5/150412 Pointed piercing elements, e.g. needles, lancets for piercing the skin blade-like piercing elements A61B5/150442
• CPC Class Codes: A61B 5/150755 Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
• CPC Class Codes: A61B 5/150824 by visual feedback
• CPC Class Codes: A61B 5/15113 Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button
• CPC Class Codes: A61B 5/15123 comprising magnets or solenoids
• CPC Class Codes: A61B 5/15151 Each piercing element being stocked in a separate isolated compartment
• CPC Class Codes: A61B 5/15161 Characterized by propelling the piercing element in a radial direction relative to the disc
• CPC Class Codes: A61B 5/15169 Characterized by a rolled strip
• CPC Class Codes: A61B 5/15171 Characterized by propelling the piercing element perpendicular to the direction of movement of the strip
• CPC Class Codes: A61B 5/15176 Stocking means comprising cap, cover, sheath or protection for aseptic stocking
• CPC Class Codes: A61B 5/15182 : Means for keeping track or checking of the total number of piercing elements already used or the number of piercing elements still remaining in the stocking, e.g. by check window, counter, display
• CPC Class Codes: A61B 5/157 : Devices characterised by integrated means for measuring characteristics of blood
• CPC Class Codes: Y10S 436/808 : Automated or kit

Abstract

A device is provided for use with a body fluid sampling device for extracting bodily fluid from an anatomical feature. The device comprises a cartridge having a plurality of cavities. The device may include a plurality of penetrating members each at least partially contained in the cavities of the cartridge wherein the penetrating members are slidably movable to extend outward from openings on the cartridge to penetrate tissue. The device may also include a plurality of analyte detecting members and a plurality of chambers. Each chamber may be associated with one of the cavities, the chambers positioned along an outer periphery of the cartridge, wherein at least one of said analyte detecting members forms a portion of one wall of one of said plurality of chambers. In one embodiment, the device may also include a fluid spreader positioned over at least a portion of said analyte detecting member to urge fluid toward one of the detecting members.

Claims

1. A device for use with a body fluid sampling device for extracting bodily fluid from an anatomical feature, said device comprising:

a cartridge having a plurality of cavities;

a plurality of penetrating members each at least partially contained in said cavities of the cartridge wherein the penetrating members are slidably movable to extend outward from openings on said cartridge to penetrate tissue;

a plurality of analyte detecting members;

a plurality of chambers, each associated with one of said cavities, said chambers positioned along an outer periphery of said cartridge;

wherein at least one of said analyte detecting members forms a portion of one wall of one of said plurality of chambers.

2. The device of claim 1 further comprising a fluid spreader positioned over at least a portion of said analyte detecting member to urge fluid toward one of the detecting members.

3. The device of claim 1 wherein said penetrating members each have a tip, wherein at least one tip has a starting position in said chamber.

4. The device of claim 1 wherein said analyte detecting members are electrochemical.

5. The device of claim 1 wherein at least one of said chamber includes an opening on one of its surfaces, said opening leading fluid to an analyte detecting member.

6. The device of claim 1 wherein at least one of said chambers includes an opening on one of its surfaces, wherein one of said analyte detecting members is contained within said opening.

7. The device of claim 1 wherein at least one of said chambers includes an opening on one of its surfaces, wherein one of said analyte detecting members is visible through said opening.

8. The device of claim 1 wherein at least one of said chambers includes an opening on one of its surfaces, wherein one of said analyte detecting members is positioned so that the opening opens directly onto the detecting member.

9. The device of claim 1 further comprising a mesh configured fluid spreader positioned over said analyte sensing member.

10. A penetrating member driver for use with a device according to claim 1.

12. The device of claim 11 further comprising a plurality of ribs, each associated with one of said sample chambers.

11. A device for use with a body fluid sampling device for extracting bodily fluid from an anatomical feature, said device comprising:

a cartridge having a plurality of sample chambers;

a plurality of penetrating members each at least partially contained in said sample chambers of the single cartridge wherein the penetrating members are slidably movable to extend outward from openings on said cartridge to penetrate tissue;

a plurality of analyte detecting members;

wherein said chamber is positioned substantially adjacent an outer periphery of said cartridge;

wherein at least one of said analyte detecting members forms a portion of one wall of one of said plurality of sample chambers.

13. A device for use with a body fluid sampling device for extracting bodily fluid from an anatomical feature, said device comprising:

a cartridge having a plurality of sample chambers;

a plurality of penetrating members each at least partially contained in said cavities of the single cartridge wherein the penetrating members are slidably movable to extend outward from openings on said cartridge to penetrate tissue;

a plurality of analyte detecting members;

wherein said chamber is positioned substantially adjacent an outer periphery of said cartridge;

at least one opening in one of said sample chambers leading fluid along a fluid path towards one of said analyte detecting members.

14. The device of claim 13 wherein said fluid path contains a channel sized to hold no more than 1 microliter.