Cosmetic preparation containing vitamin a

• US 20040096419A1
• Filed: 10/06/2003
• Published: 05/20/2004
• Est. Priority Date: 04/04/2001
• Status: Abandoned Application

• Current Assignee: COTY BV (Agnaten SE)
• Original Assignee: COTY BV (Agnaten SE)
• Inventors: Zastrow, Leonhard, Golz-Berner, Karin
• Application Number:
  US10/474,093
• Publication Number:
  US 20040096419A1
• Time in Patent Office: Days
• US Class Current: 424/74
• CPC Class Codes: A61K 2800/412 Microsized, i.e. having sizes between 0.1 and 100 microns
• CPC Class Codes: A61K 8/11 Encapsulated compositions
• CPC Class Codes: A61K 8/14 Liposomes; Vesicles
• CPC Class Codes: A61K 8/31 Hydrocarbons
• CPC Class Codes: A61K 8/671 Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
• CPC Class Codes: A61K 8/676 Ascorbic acid, i.e. vitamin C
• CPC Class Codes: A61K 8/678 Tocopherol, i.e. vitamin E
• CPC Class Codes: A61K 8/9789 Magnoliopsida [dicotyledons]
• CPC Class Codes: A61K 8/9794 Liliopsida [monocotyledons]
• CPC Class Codes: A61K 8/987 of species other than mammals or birds
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: A61Q 19/08 Anti-ageing preparations

Abstract

The invention relates to a preparation containing vitamin A and the use thereof as a cosmetic. The aim of the invention is to visibly improve the cosmetic effect of retinol or retinoides on the skin. According to the invention, the preparation comprises a retinyl derivative, a retinyl derivative encapsulated in 150-800 nm liposomes, 40-100 nm retinol microcapsules and a cherry extract, acerola, pineapple and/or bark extract from white qeubracho/silkworm extracts or a mixture thereof. The extract contains retinol or a retinyl derivative in additional to cosmetic auxiliary active ingredients, carrier active ingredients and/or other active ingredients.

Claims

1. Cosmetic preparation containing vitamin A which comprises

a) 0.001 to 1.0 percent by weight of a retinyl derivative, calculated with reference to the weight of the cosmetic preparation and selected from among retinyl palmitate, retinyl ascorbate and mixtures thereof;

and

b) 0.01 to 10 percent by weight of a retinyl derivative, selected from among retinyl palmitate, retinyl ascorbate and mixtures thereof and encapsulated in phospholipid-containing liposomes with a particle size of the liposomes in the range of 150 to 800 nm, the content of retinyl derivatives being calculated with reference to the weight of the liposomes; and

c) 0.01 to 5 percent by weight of micro-capsules with pure retinol the particle size of the capsules being in the range of 40 to 100 nm and which contain pure retinol in the range of 0.5 to 3 percent by weight, calculated with reference to the weight of the filled capsules; and

d) 0.1 to 20 percent by weight, calculated with reference to the weight of the cosmetic preparation, of an extract, selected from among the aqueous fruit extracts cherry extract (Prunus cerasus), acerola extract (Malpighia punicifolia), pineapple extract, hydrolized bark extract of Quebracho blanco, silkworm extract and mixtures of these extracts, with the content of the extract of at least one retinol compound, selected from among retinol, retinyl palmitate, retinyl ascorbate and mixtures thereof, being in the range of 0.01 to 5 percent by weight, this figure being calculated with reference to the dry weight of the extract; and

e) a rest, up to 100 percent by weight, of cosmetic auxiliaries, carrier substances and mixtures thereof.

2. Preparation according to claim 1 wherein the fruit extract is a mixture of a cherry extract with an acerola extract.

3. Preparation according to claim 1 wherein the cherry is a Spanish cherry.

4. Preparation according to claim 2 wherein the fruit extract mixture is encapsulated in capsules with a particle size of 30 to 100 μ

m.

5. Preparation according to claim 4 wherein the retinyl palmitate which is contained in the micro-capsules is provided as a mixture together with at least another vitamin, selected from among a vitamin E derivative, vitamin C, vitamin F and mixtures thereof, and carotenoides.

6. Preparation according to claim 1 wherein the retinyl derivative that is encapsulated in liposomes is retinyl palmitate.

7. Preparation according to one of the claims 1 to 6 which comprises other active ingredients, selected from among sun screens, scavengers, enzymes, active ingredient extracts of plant-based substances, oxygen-carrying fluorocarbons, magnetic single crystals with a high coercive force, kaolin modified with SiO₂ and mixtures thereof.

8. Preparation according to claim 1 which comprises in addition a cosmetic base complex consisting of an aqueous gel base and contained therein an encapsulated extract of an aqueous extraction of the pineapple fruit and the residue of an aqueous extraction of yogurt the extractions in each case having been made in the temperature range of 10 to 30°

C., the ratio pineapple extract to yogurt extract residue being in the range of 20;

80 to 80;

20 and the complex having a percentage of the enzyme Bromelin in the range of 0.1 to 1 percent by weight.

9. Use of a cosmetic preparation containing vitamin A according to one of the claims 1 to 8 as a long-term stimulant with an anti-wrinkle effect and scavenging properties.