Method of treating coronary arteries with perivascular delivery of therapetic agents
First Claim
Patent Images
1. A method of treating a stenosis or restenosis in a coronary blood vessel comprising the steps of:
- implanting a stent within the coronary blood vessel; and
injecting a therapeutic agent comprising an anti-restenosis agent into the myocardium proximate the coronary blood vessel.
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Abstract
A method of treating the intraluminal disease in a coronary artery by injecting therapeutic agents perivascularly into the myocardium near the site of disease.
73 Citations
41 Claims
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1. A method of treating a stenosis or restenosis in a coronary blood vessel comprising the steps of:
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implanting a stent within the coronary blood vessel; and
injecting a therapeutic agent comprising an anti-restenosis agent into the myocardium proximate the coronary blood vessel. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method of treating a stenosis or restenosis in a coronary blood vessel comprising the steps of:
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performing an angioplasty procedure within the coronary blood vessel; and
injecting a therapeutic agent comprising an anti-restenosis agent into the myocardium proximate the coronary blood vessel. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20)
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21. A method of treating a segment of a coronary blood vessel comprising the steps of:
injecting a therapeutic agent comprising an anti-restenosis agent into the myocardium proximate the coronary blood vessel. - View Dependent Claims (22, 23, 24, 25, 26, 27, 28, 29, 30)
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31. A method of treating intraluminal disease of a coronary blood vessel comprising the steps of:
injecting a therapeutic agent into the myocardium proximate the coronary blood vessel. - View Dependent Claims (32, 33, 34, 35, 36, 37, 38, 39, 40)
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41. A kit for delivering a therapeutic agent to a patient suffering from vascular disease characterized by a diseased treatment region in a blood vessel, said kit comprising:
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a catheter having means for introducing a therapeutic agent into in a perivascular space surrounding the blood vessel; and
a dose of therapeutic agent suitable for introduction into the perivascular space surrounding the blood vessel through the catheter;
instructions for use of the catheter according to the following method;
positioning the means for introducing into the perivascular space; and
delivering an dose of the therapeutic agent into the perivascular space near the diseased treatment region.
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Specification