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System and method for metabolyte neuronal network analysis

  • US 20040106169A1
  • Filed: 02/20/2003
  • Published: 06/03/2004
  • Est. Priority Date: 12/02/2002
  • Status: Abandoned Application
First Claim
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1. A method for determining the effects of a compound and on a neuronal cell comprising the steps of:

  • obtaining a first and a second hepatocyte supernatant, wherein the first hepatocyte supernatant comprises a supernatant from a hepatocyte exposed to a compound;

    exposing a first and second neuronal cell on a first and a second microelectrode, respectively to the first and second hepatocyte supernatants, respectively; and

    detecting the effects of the first and second hepatocyte supernatants on the first and second neuronal cells with the microelectrodes, wherein a comparison of the measurements from the first and the second microelectrodes are used to determine the effects of the hepatocyte supernatants on neuronal cells.

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