Systems and methods for treating patients with processed lipoaspirate cells
First Claim
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1. A method of treating a patient, comprising:
- (a) providing a tissue removal system;
(b) removing adipose tissue from a patient using the tissue removal system, the adipose tissue having a concentration of stem cells;
(c) processing at least a part of the adipose tissue to obtain a concentration of stem cells other than the concentration of stem cells of the adipose tissue before processing; and
(d) administering the stem cells to a patient without removing the stem cells from the tissue removal system before being administered to the patient.
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Abstract
Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.
135 Citations
92 Claims
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1. A method of treating a patient, comprising:
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(a) providing a tissue removal system;
(b) removing adipose tissue from a patient using the tissue removal system, the adipose tissue having a concentration of stem cells;
(c) processing at least a part of the adipose tissue to obtain a concentration of stem cells other than the concentration of stem cells of the adipose tissue before processing; and
(d) administering the stem cells to a patient without removing the stem cells from the tissue removal system before being administered to the patient. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39)
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40. A tissue removal system for treating a patient, comprising:
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(a) a tissue collection container including;
(i) a tissue collecting inlet port structured to receive adipose tissue removed from a patient; and
(ii) a filter disposed within the container and being structured to retain adipose tissue removed from a patient and to pass non-adipose tissue removed from the patient;
(b) a mixing container coupled to the tissue collection container to receive stem cells obtained from the adipose tissue without removal of the stem cells from the tissue removal system, and including an additive port for the administration of at least one additive to mix with the stem cells contained therein; and
(c) an outlet structured to permit the stem cells in the mixing container to be removed from the tissue collection system for administration to a patient. - View Dependent Claims (41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66)
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67. A composition for administration to a patient, comprising:
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a) a first portion of adipose tissue having a stem cell concentration;
b) a second portion of adipose tissue having a concentration of stem cells greater than the first portion of adipose tissue. - View Dependent Claims (68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79)
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80. A method of treating a patient, comprising:
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a) providing an adipose tissue removal system;
b) removing adipose tissue from a patient using the adipose tissue removal system, the adipose tissue having a concentration of stem cells; and
c) processing the adipose tissue to increase the concentration of stem cells in the adipose tissue;
d) mixing the adipose tissue having the concentrated stem cells with another portion of adipose tissue; and
e) administering the adipose tissue with the increased concentration of stem cells to a patient. - View Dependent Claims (81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92)
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Specification