Method for minimally invasive calibration of implanted pressure transducers
First Claim
Patent Images
1. A method of calibrating a pressure measurement system at least partially in pressure communication with a site within a medical patient, comprising:
- measuring a first pressure at a first location at least partially within the medical patient;
measuring a second pressure at a second location;
inducing one or more perturbations, wherein said one or more perturbations causes the first pressure to have a calculable relationship with the second pressure;
determining one or more adjustment factors based on said calculable relationship; and
adjusting said pressure measurement system based at least in part on said one or more adjustment factors.
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Abstract
This invention relates generally to apparatus and methods for the calibration of implanted pressure transducers. It is an object of several embodiments of the present invention to provide apparatus and methods for the calibration of one or more implanted pressure transducers implanted in the body of medical patients. Various embodiments of the present invention are particularly advantageous because they offer a calibration system that is less invasive than the systems currently available.
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Citations
192 Claims
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1. A method of calibrating a pressure measurement system at least partially in pressure communication with a site within a medical patient, comprising:
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measuring a first pressure at a first location at least partially within the medical patient;
measuring a second pressure at a second location;
inducing one or more perturbations, wherein said one or more perturbations causes the first pressure to have a calculable relationship with the second pressure;
determining one or more adjustment factors based on said calculable relationship; and
adjusting said pressure measurement system based at least in part on said one or more adjustment factors. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 172)
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152. A method for calibrating a pressure measurement system in pressure communication with a site inside a medical patient comprising:
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measuring a first pressure in a first location, said first location at least partially within the medical patient;
measuring at least one second pressure in at least one second location within or on said medical patient with a calibrated pressure measurement system;
inducing a perturbation of pressure substantially simultaneously at the first and at least one second locations such that the pressure measured at the at least one second location is predictive of a true pressure at the first location by a calculable relationship; and
comparing the first pressure and a prediction of the true pressure at the first location to establish at least one calibration parameter of the pressure measuring system. - View Dependent Claims (153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171)
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173. A method of calibrating a pressure measurement system located inside of a medical patient, comprising:
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measuring a first pressure at a first location, said first location located anywhere within the thoracic cavity;
measuring a second pressure at a second location that communicates with the thoracic cavity;
inducing a perturbation, wherein said perturbation causes the first pressure to have a calculable relationship with the second pressure; and
calibrating said first pressure based at least in part on said calculable relationship. - View Dependent Claims (174, 175, 176, 177)
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178. A method for calibrating a pressure measurement system located inside of a medical patient comprising:
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measuring a first pressure in a first location, said first location located anywhere within the thoracic cavity;
measuring at least one second pressure in at least one second location that communicates with the thoracic cavity;
inducing a perturbation of pressure substantially simultaneously at the first and at least one second locations such that the pressure measured at the at least one second location is predictive of a true pressure at the first location by a calculable relationship; and
using a difference between the first pressure and a prediction of true pressure at the first location to establish at least one calibration parameter of the pressure measuring system. - View Dependent Claims (179, 180, 181, 182)
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183. A method of calibrating a pressure measurement system located at least partially inside of a medical patient, comprising:
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measuring a first pressure at a first location, said first location located at least partially inside the medical patient;
measuring a second pressure at a second location;
inducing a perturbation, wherein said perturbation causes the first pressure to have a calculable relationship with the second pressure; and
calibrating said first pressure to said second pressure based at least in part on said calculable relationship. - View Dependent Claims (184)
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185. A method of calibrating a pressure measurement system located inside of a medical patient comprising:
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measuring a first pressure in a first location, said first location located within the thoracic cavity;
measuring at least one second pressure in at least one second location, wherein said second location is in pressure communication with the thoracic cavity;
inducing a perturbation of pressure substantially simultaneously at the first and at least one second locations, wherein said at least one second pressure indicates a true pressure at the first location by a calculable relationship;
determining a calibration difference between the first pressure and the at least one second pressure; and
adjusting said pressure measurement system based at least in part on said calibration difference.
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186. A method of monitoring the calibration of a pressure measurement system located at least partially inside of a medical patient, comprising:
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recording a first atmospheric pressure at a first time;
recording a second atmospheric pressure after a sampling period;
calculating the difference between the first atmospheric pressure and the second atmospheric pressure; and
providing an instruction to said medical patient based upon said difference. - View Dependent Claims (187, 188)
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189. A method of calibrating a pressure measurement system at least partially in pressure communication with a site within a medical patient, comprising:
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measuring a first pressure at a first location, said first location at least partially within the medical patient;
measuring a second pressure at a second location;
inducing a perturbation;
comparing said first pressure to said second pressure;
determining an adjustment factor based on the comparison; and
adjusting said pressure measurement system based at least in part on said adjustment factor. - View Dependent Claims (190)
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191. A method of calibrating a pressure measurement system at least partially in pressure communication with a site within a medical patient, comprising:
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measuring a first pressure at a first location, said first location within the medical patient;
measuring a second pressure at a second location;
inducing a first perturbation at a first level, wherein said first perturbation causes the first pressure to have a calculable relationship with the second pressure;
inducing at least one second perturbation at at least one second level, wherein said at least one second perturbation causes the first pressure to have said calculable relationship with the second pressure, and wherein said at least one second level is not equal to said first level;
determining one or more adjustment factors based on said calculable relationship; and
adjusting said pressure measurement system based at least in part on said one or more adjustment factors. - View Dependent Claims (192)
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Specification