Continuous glucose quantification device and method
First Claim
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1. A glucose quantification device for determining the concentration of glucose in a liquid medium comprising a reference electrode;
- a counter electrode and a working electrode with a semipermeable membrane immersed in a liquid medium in which at least one chemical entity is dissolved;
a potentiostat for applying a measurement potential to the working electrode relative to the reference electrode corresponding to a measurement voltage during at least a portion of measurement period, and thereby causing said chemical entity to participate in an electrochemical reaction at the working electrode, said electrochemical reaction resulting in a impedance measurement evoked current, a measuring unit for said impedance measurement evoked current; and
a means for comparing said impedance measurement evoked current with a predetermined value to obtain a comparison result.
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Abstract
A device and method for glucose quantification in a liquid medium using a reference electrode; a counter electrode and a working electrode with a semipermeable membrane is provided.
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11 Claims
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1. A glucose quantification device for determining the concentration of glucose in a liquid medium comprising a reference electrode;
- a counter electrode and a working electrode with a semipermeable membrane immersed in a liquid medium in which at least one chemical entity is dissolved;
a potentiostat for applying a measurement potential to the working electrode relative to the reference electrode corresponding to a measurement voltage during at least a portion of measurement period, and thereby causing said chemical entity to participate in an electrochemical reaction at the working electrode, said electrochemical reaction resulting in a impedance measurement evoked current, a measuring unit for said impedance measurement evoked current; and
a means for comparing said impedance measurement evoked current with a predetermined value to obtain a comparison result. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
- a counter electrode and a working electrode with a semipermeable membrane immersed in a liquid medium in which at least one chemical entity is dissolved;
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10. A method of modulating glucose in a patient comprising:
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a) immersing a glucose quantification device comprising a reference electrode;
a counter electrode and a working electrode with a semipermeable membrane in a liquid medium in which at least one chemical entity is present;
b) applying a measurement potential to the working electrode relative to the reference electrode to result in a impedance measurement evoked current;
c) measuring said impedance measurement evoked current;
d) comparing said impedance measurement evoked current with a predetermined value to determine whether the chemical entity in the liquid medium is within a normal range;
e) administering an amount of insulin to the patient to modulate the concentration of the chemical entity in the liquid medium and regulate glucose levels. - View Dependent Claims (11)
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Specification